T. Okuda

Publications162
h-index35
Citations4,286
Highly Influential Citations218
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Identification and characterization of the high-affinity choline transporter
In cholinergic neurons, high-affinity choline uptake in presynaptic terminals is the rate-limiting step in acetylcholine synthesis. Using information provided by the Caenorhabditis elegans Genome… Expand
Occurrence and elimination of antibiotics at four sewage treatment plants in Japan and their effects on bacterial ammonia oxidation.
The occurrence and elimination of seventeen antibiotics (three macrolides: azithromycin, clarithromycin and roxithromycin; five quinolones: ciprofloxacin, enrofloxacin, levofloxacin, nalidixic acid… Expand
Single Nucleotide Polymorphism of the Human High Affinity Choline Transporter Alters Transport Rate*
High affinity choline uptake plays a critical role in the regulation of acetylcholine synthesis in cholinergic neurons. Recently, we succeeded in molecular cloning of the high affinity choline… Expand
Development of extraction method of pharmaceuticals and their occurrences found in Japanese wastewater treatment plants.
In this study, occurrence of 66 PPCPs (pharmaceuticals and personal care products) in liquid and solid phases of sewage sludge was elucidated. The extraction methods for the PPCPs from sludge were… Expand
β-Catenin regulates excitatory postsynaptic strength at hippocampal synapses
The precise contribution of the cadherin–β-catenin synapse adhesion complex in the functional and structural changes associated with the pre- and postsynaptic terminals remains unclear. Here we… Expand
Radiation tolerance in the tardigrade Milnesium tardigradum
Purpose: Tardigrades are known to survive high doses of ionizing radiation. However, there have been no reports about radiation effects in tardigrades under culture conditions. In this study, we… Expand
Dehydration-induced expression of LEA proteins in an anhydrobiotic chironomid.
Late embryogenesis abundant (LEA) proteins are associated with desiccation tolerance in anhydrobiotic organisms. The larvae of an African chironomid, Polypedilum vanderplanki, are able to withstand… Expand
Dehydration-inducible changes in expression of two aquaporins in the sleeping chironomid, Polypedilum vanderplanki.
Aquaporin, AQP, is a channel protein that allows water to permeate across cell membranes. Larvae of the sleeping chironomid, Polypedilum vanderplanki, can withstand complete dehydration by entering… Expand
Functional characterization of the human high-affinity choline transporter.
Na(+)-dependent, high-affinity choline uptake in cholinergic neurons is the rate-limiting step in acetylcholine synthesis. Here we report the molecular cloning and functional characterization of the… Expand
The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues.
We recently cloned a trehalose transporter gene (Tret1) that contributes to anhydrobiosis induction in the sleeping chironomid Polypedilum vanderplanki Hinton. Because trehalose is the main… Expand
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