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Endogenous antimicrobial peptides and skin infections in atopic dermatitis.
BACKGROUND The innate immune system of human skin contains antimicrobial peptides known as cathelicidins (LL-37) and beta-defensins. In normal skin these peptides are negligible, but they accumulateExpand
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Innate antimicrobial peptide protects the skin from invasive bacterial infection
In mammals, several gene families encode peptides with antibacterial activity, such as the β-defensins and cathelicidins. These peptides are expressed on epithelial surfaces and in neutrophils, andExpand
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Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus.
Cathelicidins are a family of peptides thought to provide an innate defensive barrier against a variety of potential microbial pathogens. The human and mouse cathelicidins (LL-37 and CRAMP,Expand
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Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori.
BACKGROUND & AIMS LL-37/human cationic antimicrobial peptide 18 (hCAP18) is a human cathelicidin with broad-spectrum antimicrobial, lipopolysaccharide binding, and chemotactic activities. This studyExpand
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Biology and clinical relevance of naturally occurring antimicrobial peptides.
Within the last decade, several peptides have been discovered on the basis of their ability to inhibit the growth of potential microbial pathogens. These so-called antimicrobial peptides participateExpand
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Cathelicidin Antimicrobial Peptides are Expressed in Salivary Glands and Saliva
The expression of antimicrobial peptides at epithelial surfaces such as skin, lung, and intestine is thought to provide protection against infection. Cathelicidin antimicrobial peptides are essentialExpand
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Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection.
Cathelicidin antimicrobial peptides are effectors of innate immune defense in mammals. Humans and mice have only one cathelicidin gene, whereas domesticated mammals such as the pig, cow, and horseExpand
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ABSTRACT The solvent extraction of alkali and alkaline earth metals (Li, Na, K, Mg, Ca) was studied using organophosphorus compounds like di-2-ethylhexylphosphoric acid(D2EHPA) orExpand
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Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin.
The eccrine gland is one of the major cutaneous appendages and secretes sweat. Its principal function is thermoregulation during exposure to a hot environment or physical exercise. In addition toExpand
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Extraction Equilibria of Amino Acids with Quaternary Ammonium Salt
The extraction equilibria of various amino acids with tri-n-octylmethylammonium chloride (TOMAC) were studied in the high pH range. TOMAC reacted with the anion of amino acid and OH– according to theExpand
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