T. Noguchi

Publications49
h-index20
Citations1,367
Highly Influential Citations28
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The nocturnal secretion of cardiac natriuretic peptides during obstructive sleep apnoea and its response to therapy with nasal continuous positive airway pressure
The nocturnal secretion profile of the newly identified natriuretic peptide (NP), brain natriuretic peptide (BNP), was studied in 14 patients with obstructive sleep apnoea syndrome (OSAS) (apnoea… Expand
  • 104
  • 6
Pharmacokinetics of cefpiramide (SM-1652) in humans.
The pharmacokinetics of cefpiramide (SM-1652) were studied after the intravenous administration of single or multiple doses to 21 healthy volunteers. The cefpiramide concentration in plasma at time… Expand
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Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndrome.
  • K. Chin, M. Ohi, +5 authors K. Kuno
  • Medicine
  • American journal of respiratory and critical care…
  • 1 June 1996
In patients with obstructive sleep apnea syndrome (OSAS), the blood coagulation system may contribute to an increased risk of cardiovascular events, which occur most frequently in the morning. Nasal… Expand
  • 237
  • 2
Norepinephrine, but not epinephrine, enhances platelet reactivity and coagulation after exercise in humans.
The effects of exercise and catecholamines on platelet reactivity or coagulation and fibrinolysis appear to be inconsistent. This may be partly due to the methods employed in previous studies. In the… Expand
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Effect of dietary proteins on the plasma immunoreactive insulin-like growth factor-1/somatomedin C concentration in the rat.
Plasma immunoreactive insulin-like growth factor-1/somatomedin C (IR-IGF-1) was determined in rats fed for 1 week on a protein-free diet, or diets containing gluten, gluten supplemented with lysine… Expand
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Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents
OBJECTIVE:Isomerized hop extract (IHE), which consists mainly of isohumulones and is required in the beer brewing process, was investigated for its effects on diet-induced obesity in two strains of… Expand
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An experimental system designed to study the in situ intestinal lymphatic transport of lipophilic drugs in anesthetized rats
Abstract An experimental system has been developed that enables an estimate of the lymphatic transport of DDT (1,1-bis( p -chlorophenyl)-2,2,2-trichloroet p , p -DDT) by the small intestine. The… Expand
  • 44
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The effect of drug lipophilicity and lipid vehicles on the lymphatic absorption of various testosterone esters
Abstract Mesenteric lymph was collected from non-restrained unanesthetized rats following oral administration of several different testosterone esters dissolved in various non-polar lipid vehicles. A… Expand
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The Adreno‐Sympathetic System, the Genetic Predisposition to Hypertension, and Stress
The blood pressure, heart rate, and plasma cate-cholamine (CA) response to standing and mental stresses were studied in 14 normotensive subjects with normotensive parents (PNT group), 14 normotensive… Expand
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Lymphatic appearance of DDT in thoracic or mesenteric lymph duct cannulated rats
Abstract Lymphatic absorption studies were conducted in rats using DDT (2,2-bis( P -chlorophenyl)1,1,1-trichloroethane; p,p-DDT) as a lymphatically absorbed model compound. The lymphatic appearance… Expand
  • 48
  • 1