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Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart
About 3,000 individuals in the United States are awaiting a donor heart; worldwide, 22 million individuals are living with heart failure. A bioartificial heart is a theoretical alternative toExpand
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Sniffing controls an adaptive filter of sensory input to the olfactory bulb
Most sensory stimuli are actively sampled, yet the role of sampling behavior in shaping sensory codes is poorly understood. Mammals sample odors by sniffing, a complex behavior that controls odorantExpand
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Synchronization in hybrid neuronal networks of the hippocampal formation.
Understanding the mechanistic bases of neuronal synchronization is a current challenge in quantitative neuroscience. We studied this problem in two putative cellular pacemakers of the mammalianExpand
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Epilepsy in Small-World Networks
In hippocampal slice models of epilepsy, two behaviors are seen: short bursts of electrical activity lasting 100 msec and seizure-like electrical activity lasting seconds. The bursts originate fromExpand
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Seizure prediction with spectral power of EEG using cost‐sensitive support vector machines
Purpose:  We propose a patient‐specific algorithm for seizure prediction using multiple features of spectral power from electroencephalogram (EEG) and support vector machine (SVM) classification.
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Beyond Two-Cell Networks: Experimental Measurement of Neuronal Responses to Multiple Synaptic Inputs
Oscillations of large populations of neurons are thought to be important in the normal functioning of the brain. We have used phase response curve (PRC) methods to characterize the dynamics of singleExpand
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Electric field suppression of epileptiform activity in hippocampal slices.
1. The effects of relatively small external DC electric fields on synchronous activity in CA1 and CA3 from transverse and longitudinal type hippocampal slices were studied. 2. To record neuronalExpand
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Identification of the hippocampal input to medial prefrontal cortex in vitro.
To delineate the cellular mechanisms underlying the function of medial prefrontal cortex (mPFC) networks, it is critical to understand how synaptic inputs from various afferents are integrated andExpand
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Synchronization from Second Order Network Connectivity Statistics
We investigate how network structure can influence the tendency for a neuronal network to synchronize, or its synchronizability, independent of the dynamical model for each neuron. The synchronyExpand
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  • Open Access