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[Effects of pesticides on cytokines production by human peripheral blood mononuclear cells--fenitrothion and glyphosate].
- K. Nakashima, T. Yoshimura, F. Yamazaki
- BiologyChudoku kenkyu : Chudoku Kenkyukai jun kikanshi…
- 1 April 2002
It is suggested that pesticides inhibit the immune system differently, and the grasp of immune condition might be useful for the prognostic presumption and the infectious danger of degree in patients with pesticides poisoning.
Immunomodulatory action of levofloxacin on cytokine production by human peripheral blood mononuclear cells.
Results show that LVFX has an immunomodulatory action on cytokines production by PBMC independent of its antimicrobial activity.
Effects of cAMP-phosphodiesterase isozyme inhibitor on cytokine production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells.
Inhibition of tumor necrosis factor-alpha and interleukin-1-beta production by beta-adrenoceptor agonists from lipopolysaccharide-stimulated human peripheral blood mononuclear cells.
Beta-agonists inhibit the production of proinflammatory cytokines, such as TNF-alpha and IL-1 beta, by elevating intracellular cAMP levels, which might be beneficial in the treatment of allergic inflammation.
Effect of Theophylline on the Production of Interleukin-1β, Tumor Necrosis Factor-α, and Interleukin-8 by Human Peripheral Blood Mononuclear Cells
Suppression of the production of IL-1β and TNF-α by therapeutic levels of theophylline suggested that this drug might have anti-inflammatory and immunosuppressive effects.
Modulation of Th1- and Th2-like cytokine production from mitogen-stimulated human peripheral blood mononuclear cells by phosphodiesterase inhibitors.
Increased in vitro release of interferon-gamma from ampicillin-stimulated peripheral blood mononuclear cells in Stevens-Johnson syndrome.
- T. Yoshimura, E. Hamaguchi, F. Yamazaki
- Medicine, BiologyBiological & pharmaceutical bulletin
- 1 June 2004
Increased in vitro IFN-gamma release was observed on ampicillin-stimulated PBMCs, which may indicate the role of ampiculin as the drug responsible for the induction of SJS, and may imply therole of IFN -gamma in the pathogenesis of S JS.
Increased antibody levels to desmogleins 1 and 3 after administration of carbamazepine
It was found that anti‐Dsg1 and anti-Dsg3 antibody titres were increased in three individuals administered carbamazepine, and these findings might be helpful for preventing susceptible individuals from exposure to the suspect drugs.
Adherence and awareness of the therapeutic intent of oral anticancer agents in an outpatient setting.
For patients treated with S-1 or capecitabine, the type and therapeutic purpose of oral anticancer agents did not affect medication adherence, and patient guidance by pharmacists is important, as it may result in improved medication adherence and an improved understanding of the treatment side-effects in patients self-administering prescribed drugs.
Oral anticancer agent medication adherence by outpatients
Overall, the medication compliance of the patients taking the oral anticancer agents was good, but the medication adherence was insufficient, and a better understanding of the effectiveness and necessity of drugs and their side-effects is required.