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Programmed cell death protein 1 expression is an independent prognostic factor in gastric cancer after curative resection
TLDR
PD-1 expression is associated with a poor prognosis and is correlated with PD-L1 and Foxp3 expression in patients with gastric cancer. Expand
Irinotecan injures tight junction and causes bacterial translocation in rat.
TLDR
Irinotecan causes disorders in the intestinal epithelial barrier and induces bacterial translocation in rats and injures claudin-1 and occludin. Expand
Expression of thrombospondin-1 and Ski are prognostic factors in advanced gastric cancer
TLDR
This study shows that TSP-1 enhances angiogenesis due to its positive correlation with VEGF and MVD, and is a good prognostic factor for survival in advanced gastric cancer. Expand
Intraperitoneal infusion of paclitaxel with S-1 for peritoneal metastasis of advanced gastric cancer: phase I study.
TLDR
Maximum tolerated dose (MTD), dose limiting toxicity (DLT) and recommended dose (RD) of intraperitoneally infused paclitaxel (PTX) with S-1 as a phase I study were determined and PTX concentrations in the ascites were supported by pharmocokinetics of PTX. Expand
The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric cancer.
TLDR
CD133 expression and ThBS1 expression were prognostic factors, and a negative relationship between HDAC and THBS1 was observed in advanced gastric cancer, and these biomarkers may help determine postoperative treatment in patients with Gastric cancer. Expand
Limited lymph node dissection in elderly patients with gastric cancer.
TLDR
Investigation of the impact of age on postoperative outcome and the effect of limited lymph node dissection for elderly patients found limited lymph nodes dissection did not affect the cancer-specific survival in elderly patients. Expand
Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer.
TLDR
Several genes likely to be useful for establishing individualized therapies for patients with rectal cancer are identified. Expand
Kampo medicine “Dai-kenchu-to” prevents CPT-11-induced small-intestinal injury in rats
TLDR
DKT suppressed CPT-11 induced inflammatory cytokines and apoptosis in the intestinal mucosa and maintained the mucosal integrity and improved interleukin-1β and IFN-γ expression by DKT. Expand
Huge splenic epidermoid cyst with elevation of serum CA19-9 level.
TLDR
The case of a very rare, huge epidermoid cyst of the spleen suggests that measurement of the serum CA19-9 level is useful for evaluating therapeutic efficacy of a splenic epidermite cyst. Expand
Duodenal-jejunal bypass changes the composition of the gut microbiota
TLDR
DJB changes the composition of gut microbiota; these changes might be the factors that contribute to the effects of DJB. Expand
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