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Loss of claudin-1 expression correlates with malignancy of hepatocellular carcinoma.
BACKGROUND The prognosis for the hepatocellular carcinoma (HCC) patient is affected by invasion and metastases. The attenuated expression of adherens junction protein epithelial-cadherin (E-cad)Expand
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Phylogenetic Analysis of Bacteria Preserved in a Permafrost Ice Wedge for 25,000 Years
ABSTRACT Phylogenetic analysis of bacteria preserved within an ice wedge from the Fox permafrost tunnel was undertaken by cultivation and molecular techniques. The radiocarbon age of the ice wedgeExpand
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Downregulation of EphA7 by hypermethylation in colorectal cancer
A significant reduction of EphA7 expression in human colorectal cancers was shown using semiquantitative reverse transcription–polymerase chain reaction analysis in 59 colorectal cancer tissues,Expand
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Hepatic Inflammatory Pseudotumor Mimicking Intrahepatic Cholangiocarcinoma: Report of a Case
Hepatic inflammatory pseudotumor (IPT) is a relatively rare lesion comprised of proliferating fibrovascular tissue infiltrated by inflammatory cells. IPT has a potential for recurrence and persistentExpand
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Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer
Evidence suggests that the erythropoietin‐producing hepatocellular (EPH) receptor tyrosine kinases (RTKs) and their ephrin (EFN) ligands are involved in human carcinogenesis. Expression of two ofExpand
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Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4
The identification of cancer biomarkers is critical for target‐linked cancer therapy. The overall level of phosphatidylcholine (PC) is elevated in colorectal cancer (CRC). To investigate whichExpand
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RSPO fusion transcripts in colorectal cancer in Japanese population
R-spondin (RSPO) gene fusions have recently been discovered in a subset of human colorectal cancer (CRC) in the U.S. population; however, whether the fusion is recurrent in CRC arising in patientsExpand
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Nutritional therapy versus 6-mercaptopurine as maintenance therapy in patients with Crohn's disease.
BACKGROUND 6-Mercaptopurine is often used as maintenance therapy in patients with Crohn's disease. However, toxicities like myelosuppression limit its clinical benefit. AIMS To evaluate theExpand
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Bax is downregulated in inflamed colonic mucosa of ulcerative colitis
BACKGROUND AND AIMS One form of epithelial cell injury in inflamed colonic mucosa in ulcerative colitis (UC) is reported to involve apoptosis of these cells. Bcl-2 family proteins Bax and Bcl-2 areExpand
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Functional outcome of stapled ileal pouch-anal canal anastomosis versus handsewn pouch-anal anastomosis
This study was conducted to determine whether stapled ileal pouch-anal canal anastomosis (IACA) preserving the anal transitional zone (ATZ) or hand-sewn ileal pouch-anal anastomosis with mucosectomyExpand
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