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Endobronchial lipoma: review of 64 cases reported in Japan.
BACKGROUND Several recent studies discuss bronchoscopic techniques for treating endobronchial lipoma, an extremely rare benign tumor. OBJECTIVES To describe the epidemiology of endobronchial lipoma… Expand
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells
- K. Matsushima, H. Isomoto, +18 authors K. Nakao
- Biology, Medicine
- Journal of Translational Medicine
- 22 March 2011
BackgroundEsophageal squamous cell carcinoma (ESCC) is often diagnosed at later stages until they are incurable. MicroRNA (miR) is a small, non-coding RNA that negatively regulates gene expression… Expand
Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors
Background: The signal transducer and activator of transcription 3 (STAT3) is a key signalling molecule implicated in the regulation of growth and malignant transformation. Constitutive activation of… Expand
Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
- Y. Maeda, T. Tsuchiya, +9 authors J. Whitsett
- Medicine, Biology
- The Journal of clinical investigation
- 3 December 2012
Mucinous adenocarcinoma of the lung is a subtype of highly invasive pulmonary tumors and is associated with decreased or absent expression of the transcription factor NK2 homeobox 1 (NKX2-1; also… Expand
Modified Japan Integrated Staging is currently the best available staging system for hepatocellular carcinoma patients who have undergone hepatectomy
BackgroundWe previously reported the effectiveness of the modified Cancer of the Liver Italian Program (CLIP) score in hepatocellular carcinoma (HCC) staging. To determine the best predictive staging… Expand
The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
We previously identified SMYD3 as a histone methyltransferase and showed that its expression was elevated in colorectal, hepatocellular, and breast carcinomas. In the investigation of… Expand
Gene signature driving invasive mucinous adenocarcinoma of the lung
Though invasive mucinous adenocarcinoma of the lung (IMA) is pathologically distinctive, the molecular mechanism driving IMA is not well understood, which hampers efforts to identify therapeutic… Expand
Assessment and follow-up of intercostal nerve damage after video-assisted thoracic surgery.
- T. Miyazaki, T. Sakai, +5 authors T. Nagayasu
- European journal of cardio-thoracic surgery…
- 1 June 2011
OBJECTIVE Chronic pain is a common complication after thoracic surgery. The most important factor appears to be intercostal nerve damage. The purpose of this prospective study was to objectively… Expand
Low frequency of BRAFT1796A mutations in childhood thyroid carcinomas.
- Atsushi Kumagai, H. Namba, +13 authors S. Yamashita
- The Journal of clinical endocrinology and…
- 1 September 2004
A high prevalence of the activating BRAF mutation, BRAF(T1796A), is observed in adult papillary thyroid carcinomas (PTCs). The prognosis of childhood PTCs is generally fairly good despite the fact… Expand
High expression of trimethylated histone H3 at lysine 27 predicts better prognosis in non-small cell lung cancer.
- X. Chen, Ning Song, +7 authors T. Koji
- Biology, Medicine
- International journal of oncology
- 1 November 2013
Epigenetic parameters such as DNA methylation and histone modifications play pivotal roles in carcinogenesis. Global histone modification patterns have been implicated as possible predictors of… Expand