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Scratching behavior induced by pruritogenic but not algesiogenic agents in mice.
The results suggest that compound 48/80- and substance P-induced scratching of the injected site is due to itch, but not to pain, and that histamine produces itch in the mouse. Expand
Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice
- Tomomi Yamaguchi, T. Nagasawa, M. Satoh, Y. Kuraishi
- Medicine, Chemistry
- Neuroscience Research
- 1 November 1999
The results suggest that scratching induced by intradermal injection of 5-HT is itch-associated response, and the 5-ht action may be mediated at least partly by cutaneous 5- HT2 receptors. Expand
Factors influencing EPA+DHA levels in red blood cells in Japan.
Multivariate analysis indicated that there were significant correlations between RBC EPA+DHA and age, age, gender, gender and physical activity but not with body mass index or smoking. Expand
Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice.
- T. Andoh, T. Nagasawa, M. Satoh, Y. Kuraishi
- Medicine, Chemistry
- The Journal of pharmacology and experimental…
- 1 September 1998
The results suggest that scratching of the mouse induced by an i.d. injection of SP is itch-associated response, and the SP action may be mediated at least partly by cutaneous NK1 receptors, and mast cells may not be key factors in SP-induced itching. Expand
The Effect of Docosahexaenoic Acid on Aggression in Elderly Thai Subjects—a Placebo-controlled Double-blind Study
- T. Hamazaki, A. Thienprasert, Kanit Kheovichai, Suched Samuhaseneetoo, T. Nagasawa, Shiro Watanabe
- Nutritional neuroscience
- 1 January 2002
The DHA administration favorably controlled extraggression in at least elderly white-collar workers and in the group of villagers, there was no significant difference between the control and DHA groups in extragression. Expand
Prostaglandins, Leukotrienes and Essential Fatty Acids
It is suggested that the presence of 20:3n-9 in cartilage may be related to its vesselfree status and that it may be useful for the treatment of disorders with excessive vasculature. Expand
Tannins and Related Compounds. I. Rhubarb (1)
Three new tannin-related compounds (I, II and III), along with lindleyin (IV), (+)-catechin, 3-O-galloyl-(-)-epicatechin, gallic acid, 3, 5, 4'-trihydroxystilbene… Expand
Expression of tachykinin NK1 receptor mRNA in dorsal root ganglia of the mouse.
The present results suggest that NK1 receptor mRNA is expressed in the mouse DRG, although the level is relatively low. Expand
Isolation and Characterization of Phenolic Compounds from Coptidis Rhizoma
Six phenolic compounds were isolated from Coptidis Rhizoma and were identified as 3-(3', 4'-dihydroxyphenyl)-(2R)-lactic acid, 3-(3', 4'-dihydroxyphenyl)-(2R)-lactic acid 4'-O-β-D-glucopyranoside,… Expand
Helicobacter pylori alters n‐6 fatty acid metabolism and prostaglandin E2 synthesis in rat gastric mucosal cells
- A. Nakaya, H. Wakabayashi, +9 authors A. Watanabe
- Biology, Medicine
- Journal of gastroenterology and hepatology
- 1 November 2001
This study aimed to find out whether n‐6 long chain polyunsaturated fatty acids from linoleic acid are formed in RGM‐1 cells, and investigated the effect of H. pylori broth culture filtrates on this point. Expand