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Urinary-cell mRNA profile and acute cellular rejection in kidney allografts.
BACKGROUND The standard test for the diagnosis of acute rejection in kidney transplants is the renal biopsy. Noninvasive tests would be preferable. METHODS We prospectively collected 4300 urineExpand
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Messenger RNA for FOXP3 in the urine of renal-allograft recipients.
BACKGROUND The outcome of renal transplantation after an episode of acute rejection is difficult to predict, even with an allograft biopsy. METHODS We studied urine specimens from 36 subjects withExpand
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The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology
The XIII Banff meeting, held in conjunction the Canadian Society of Transplantation in Vancouver, Canada, reviewed the clinical impact of updates of C4d‐negative antibody‐mediated rejection (ABMR)Expand
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Treatment-related acute renal failure in the elderly: a hospital-based prospective study.
BACKGROUND Elderly individuals need a host of diagnostic procedures and therapeutic interventions to take care of ailments. This prospective study was carried out to determine the magnitude ofExpand
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MicroRNA Sequence Profiles of Human Kidney Allografts With or Without Tubulointerstitial Fibrosis
Background MicroRNA (miRNA) alterations accompanying interstitial fibrosis and tubular atrophy (IFTA) in kidney allografts may point toward pathologic mechanisms. Small-RNA sequencing providesExpand
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Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine1
Background. Polyoma virus type BK (BKV) nephritis has emerged as an important cause of renal allograft dysfunction and graft failure. Its diagnosis is contingent on the invasive procedure ofExpand
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Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine.
BACKGROUND We explored the hypothesis that measurements of mRNA encoding interferon-inducible protein-10 (IP-10) or the chemokine receptor CXCR3 in urinary cells offer a noninvasive means ofExpand
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Independent Risk Factors for Urinary Tract Infection and for Subsequent Bacteremia or Acute Cellular Rejection: A Single-Center Report of 1166 Kidney Allograft Recipients
Background Urinary tract infection (UTI) is a frequent, serious complication in kidney allograft recipients. Methods We reviewed the records of 1166 kidney allograft recipients who received theirExpand
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Acute renal failure due to rifampicin: a study of 25 patients.
BACKGROUND Acute renal failure (ARF) caused by rifampicin typically occurs on intermittent administration. There are isolated case reports and only one series reported in the literature. SystematicExpand
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MicroRNAs: Small RNAs With Big Effects
MicroRNAs (miRNAs) are evolutionarily conserved, small (∼20-25 nucleotides), single-stranded molecules that suppress the expression of protein-coding genes by translational repression, messenger RNAExpand
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