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Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy.
One of the major obstacles to the successful treatment of cancer is the complex biology of solid tumour development. Although regulation of intracellular pH has been shown to be critically importantExpand
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Superparamagnetic iron oxide–enhanced magnetic resonance images of hepatocellular carcinoma: Correlation with histological grading
Superparamagnetic iron oxide (SPIO)–enhanced magnetic resonance (MR) imaging has been used for the detection of hepatic tumors. However, little is known about this technique in relation toExpand
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Hypervascular hepatocellular carcinoma: detection with double arterial phase multi-detector row helical CT.
PURPOSE To assess whether double arterial phase imaging with multi-detector row helical computed tomography improves detection of hypervascular hepatocellular carcinoma (HCC). MATERIALS AND METHODSExpand
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Detectability of hypervascular hepatocellular carcinoma by arterial phase images of MR and spiral CT.
The ability of arterial phase images of breath-hold MR imaging and spiral CT to detect hypervascular hepatocellular carcinomas (HCCs) was evaluated. Prior to transcatheter arterial chemoembolizationExpand
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A short form of leptin receptor performs signal transduction.
The obese (ob) gene product, leptin, a peptide hormone, which is synthesized in adipocytes, is a satiety factor and is involved in the control of body weight via the regulation of energy homeostasis.Expand
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PHYTOCHROME-DEPENDENT LATE-FLOWERING accelerates flowering through physical interactions with phytochrome B and CONSTANS
Significance In plants, red light and blue light have antagonistic functions for the regulation of a flowering activator, CONSTANS (CO). Recently, direct regulation of CO by blue light photoreceptorsExpand
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Enhanced Expression of the Human Vacuolar H+-ATPase c subunit Gene (ATP6L) in Response to Anticancer Agents*
We have isolated two overlapping genomic clones that contain the 5′-terminal portion of the human vacuolar H+-ATPase c subunit (ATP6L) gene. The sequence preceding the transcription initiation site,Expand
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Imaging evaluation of the cirrhotic liver.
Because recent advances in medical care decrease the mortality rate due to liver cirrhosis itself, many cirrhotic patients die due to hepatocellular carcinoma. Accordingly, the role of radiology inExpand
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Promoter and 11-kilobase upstream enhancer elements responsible for hepatoma cell-specific expression of the rat ornithine transcarbamylase gene.
The gene for ornithine transcarbamylase (OTC; EC, a urea cycle enzyme, is expressed almost exclusively in the liver and small intestine. To identify DNA elements regulating transcription ofExpand
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Mutations in nonstructural protein 5A gene and response to interferon in hepatitis C virus genotype 2 infection
An association has been reported between mutations in the amino acid residues 2209‐2248 of the nonstructural protein 5A (NS5A) gene (interferon‐sensitivity determining region [ISDR]) and interferonExpand
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