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The genome of the social amoeba Dictyostelium discoideum
A proteome-based phylogeny shows that the amoebozoa diverged from the animal–fungal lineage after the plant–animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral genome than have plants, animals or fungi.
Comparative genomics reveals insights into avian genome evolution and adaptation
This work explored bird macroevolution using full genomes from 48 avian species representing all major extant clades to reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits.
The Human Genome Project reveals a continuous transfer of large mitochondrial fragments to the nucleus.
Fifty thousand years of Arctic vegetation and megafaunal diet
The authors' analyses indicate that both graminoids and forbs would have featured in megafaunal diets, and question the predominance of a Late Quaternary graminoid-dominated Arctic mammoth steppe.
Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy
The ecological niches occupied by these species are influenced by a relatively small number of gene products which operate at the host-parasite interface and that the dominance of vertical transmission in N. caninum may be associated with the evolution of reduced virulence in this species.
The biology of intron gain and loss.
Evidence is discussed that differences in intron densities in eukaryote genomes are subject to selection acting on introns depending on the biology of the organism and the gene involved.
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites
Insight is provided into how obligate parasites with diverse life strategies arose from a once free-living phototrophic marine alga, and co-regulated with genes encoding the flagellar apparatus supporting the functional contribution of flagella to the evolution of invasion machinery.
Eukaryotic Intron Loss
It is shown here that intron-poor eukaryotes for which genome data is available have a 5′ bias in the position of their introns within genes.
The genomic and phenotypic diversity of Schizosaccharomyces pombe
The fission yeast Schizosaccharomyces pombe is an important model for eukaryotic biology, but researchers typically use one standard laboratory strain, so this analysis represents a rich resource to examine genotype-phenotype relationships in a tractable model.
Statistical evidence for miscoding lesions in ancient DNA templates.
- A. Hansen, E. Willerslev, C. Wiuf, T. Mourier, P. Arctander
- Biology, MedicineMolecular biology and evolution
- 1 February 2001
A statistical model for analyzing PCR-mediated base-misincorporations, catalyzed by the commonly used Thermus aquaticus (Taq) polymerase enzyme, in amplification products from fossil remains is presented.