• Publications
  • Influence
Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy.
  • T. Moffitt
  • Psychology, Medicine
  • Psychological review
  • 1 October 1993
TLDR
It is suggested that delinquency conceals 2 distinct categories of individuals, each with a unique natural history and etiology: a small group engages in antisocial behavior of 1 sort or another at every life stage, whereas a larger group is antisocial only during adolescence. Expand
Role of Genotype in the Cycle of Violence in Maltreated Children
TLDR
A functional polymorphism in the gene encoding the neurotransmitter-metabolizing enzyme monoamine oxidase A was found to moderate the effect of maltreatment, and it was found that Maltreated children with a genotype conferring high levels of MAOA expression were less likely to develop antisocial problems. Expand
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
TLDR
Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup. Expand
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene.
TLDR
Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup. Expand
A gradient of childhood self-control predicts health, wealth, and public safety
TLDR
Following a cohort of 1,000 children from birth to the age of 32 y, it is shown that childhood self-control predicts physical health, substance dependence, personal finances, and criminal offending outcomes, following a gradient of self- control. Expand
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account. Expand
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades. Expand
Developmental trajectories of childhood disruptive behaviors and adolescent delinquency: a six-site, cross-national study.
TLDR
The results indicate that among boys there is continuity in problem behavior from childhood to adolescence and that such continuity is especially acute when early problem behavior takes the form of physical aggression. Expand
Development of depression from preadolescence to young adulthood: emerging gender differences in a 10-year longitudinal study.
TLDR
Results suggest that middle-to-late adolescence (ages 15-18) may be a critical time for studying vulnerability to depression because of the higher depression rates and the greater risk for depression onset and dramatic increase in gender differences in depression during this period. Expand
Males on the life-course-persistent and adolescence-limited antisocial pathways: Follow-up at age 26 years
TLDR
Findings support the theory of life-course-persistent and adolescence-limited antisocial behavior but also extend it, and recommend intervention with all aggressive children and with all delinquent adolescents, to prevent a variety of maladjustments in adult life. Expand
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