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Perivascular Epithelioid Cell Neoplasms of Soft Tissue and Gynecologic Origin: A Clinicopathologic Study of 26 Cases and Review of the Literature
PEComas, occasionally associated with the tuberous sclerosis complex, are defined by the presence of perivascular epithelioid cells that coexpress muscle and melanocytic markers. This family of
Most Osteomalacia-associated Mesenchymal Tumors Are a Single Histopathologic Entity: An Analysis of 32 Cases and a Comprehensive Review of the Literature
TLDR
Most cases of mesenchymal tumor-associated OO, both in the present series and in the reported literature, are due to PMTMCT, and improved recognition of their histologic spectrum, including the presence of bone or osteoid-like matrix in otherwise typical cases and the existence of malignant forms, should allow distinction from other meschymal tumors.
Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant.
TLDR
The poorly recognized low-grade myxofibrosarcoma is emphasized, as proper diagnosis and treatment and scrupulous follow-up are mandatory to avoid local recurrence and gradual tumor progression to a higher-grade neoplasm that may then metastasize.
Myopericytoma of Skin and Soft Tissues: Clinicopathologic and Immunohistochemical Study of 54 Cases
TLDR
Myopericytoma represents a distinct perivascular, myoid neoplasm of skin and soft tissues, characterized by a broad morphologic spectrum of concentrically, periv vascularly growing myoid tumor cells that stain positively for ASMA and often for h-caldesmon, whereas desmin is usually negative.
Low-grade myofibroblastic sarcoma: analysis of 18 cases in the spectrum of myofibroblastic tumors.
TLDR
Low-grade myofibroblastic sarcoma seems to represent a distinct entity in the spectrum of low-gradeMyofibrosarcoma neoplasms and is distinguishable from fibromatosis, my ofibrom atosis, solitary fibrous tumor, fibrosar coma, and leiomyosarcomA.
Epithelioid hemangioendothelioma of skin and soft tissues: clinicopathologic and immunohistochemical study of 30 cases.
TLDR
It is suggested that EHE of soft tissue is better regarded as a fully malignant, rather than borderline, vascular neoplasm, albeit the prognosis is better than in conventional angiosarcoma.
Fibrosarcomatous ("high-grade") dermatofibrosarcoma protuberans: clinicopathologic and immunohistochemical study of a series of 41 cases with emphasis on prognostic significance.
TLDR
Fibrosarcomatous change in DFSP represents a form of tumor progression inDFSP and is associated with a significantly more aggressive clinical course than in ordinary DFSP, indicating a possible need for treatment intensification in such cases.
Pleomorphic Rhabdomyosarcoma in Adults: A Clinicopathologic Study of 38 Cases with Emphasis on Morphologic Variants and Recent Skeletal Muscle-Specific Markers
TLDR
It is shown that PRMS, a tumor of predominantly middle-aged adult males in the lower extremity, can be diagnosed by the morphologic presence of scattered PRMB with immunohistochemical evidence of at least one skeletal muscle-specific marker.
Mucinous Carcinoma of the Skin, Primary, and Secondary: A Clinicopathologic Study of 63 Cases With Emphasis on the Morphologic Spectrum of Primary Cutaneous Forms: Homologies With Mucinous Lesions in
TLDR
It is demonstrated that primary cutaneous mucinous carcinomas span a morphologic spectrum compatible to their mammary counterparts, and most lesions seem to originate from in situ lesions that may represent, using mammary pathology terminology, ductal hyperplasia, atypical ductal Hyperplasia or ductal carcinoma in situ or a combination of the three.
Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma
TLDR
The link between cellular angiofibroma, spindle cell lipoma, and mammary-type myofibroblastoma is affirm, showing a spectrum of one entity with morphological variations dependent on anatomic location.
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