• Publications
  • Influence
Polynesian genetic affinities with Southeast Asian populations as identified by mtDNA analysis.
Polynesian genetic affinities to populations of Asia were studied using mtDNA markers. A total of 1,037 individuals from 12 populations were screened for a 9-bp deletion in the intergenic region
Genetic evidence for the proto-Austronesian homeland in Asia: mtDNA and nuclear DNA variation in Taiwanese aboriginal tribes.
TLDR
The results suggest that the Taiwanese have temporally deep roots, probably in central or south China, and have been isolated from other Asian populations in recent history.
Mitochondrial DNA Heteroplasmy.
  • T. Melton
  • Medicine, Biology
    Forensic science review
  • 2004
TLDR
It is concluded that heteroplasmy can be expected to play a role in forensic interpretation on a regular basis, and that knowledge of its biological underpinnings contribute to just, conservative, and scientifically appropriate interpretational guidelines.
Routine Forensic Use of the Mitochondrial 12S Ribosomal RNA Gene for Species Identification
TLDR
The use of this assay has halved the number of samples for which no mtDNA results are obtained and is especially useful on hairs and degraded samples.
Forensic Mitochondrial DNA Analysis: Current Practice and Future Potential.
TLDR
It is important to periodically reassess the alternative methods available to the mtDNA practitioner, and to evaluate newer technologies being put forth by the scientific community, for example, next-generation sequencing.
Extent of heterogeneity in mitochondrial DNA of sub-Saharan African populations.
TLDR
Overall, when considering both the low diversity within some populations and high heterogeneity among populations, SSO typing of mtDNA may not be a desirable forensic DNA typing method for continental African populations.
Forensic mitochondrial DNA analysis of 691 casework hairs.
TLDR
A five year retrospective review of mitochondrial DNA analysis on 691 casework hairs was carried out, and the likelihood of obtaining a full profile decreased, although "mini-primer sets" could often be used to capture a partial profile.
Forensic mitochondrial DNA analysis: two years of commercial casework experience in the United States.
TLDR
MtDNA forensic analysis in the private sector was successfully applied to many different types of samples overall, with minimal rates of complication due to sample handling challenges and sequence-specific phenomena.
Extent of heterogeneity in mitochondrial DNA of European populations.
TLDR
Overall, there is no statistically significant heterogeneity for European populations (p > 0.001), and these groups are virtually indistinguishable with respect to mtDNA SSO types, demonstrating the utility of mtDNA typing for forensic investigations.
Diversity and heterogeneity in mitochondrial DNA of North American populations.
TLDR
Overall mtDNA is a satisfactory forensic typing locus within broadly defined African- American, European-American, and Hispanic groups from North America, based on the high diversity estimates and absence of heterogeneity, as characterized by SSO typing.
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