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Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma
Whereas uncoupling protein 1 (UCP-1) is clearly involved in thermogenesis, the role of UCP-2 is less clear. Using hybridization, cloning techniques and cDNA array analysis to identify inducibleExpand
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Tad1p, a yeast tRNA‐specific adenosine deaminase, is related to the mammalian pre‐mRNA editing enzymes ADAR1 and ADAR2
We have identified an RNA‐specific adenosine deaminase (termed Tad1p/scADAT1) from Saccharomyces cerevisiae that selectively converts adenosine at position 37 of eukaryotic tRNAAla to inosine. TheExpand
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Clinical development of new drug–radiotherapy combinations
In countries with the best cancer outcomes, approximately 60% of patients receive radiotherapy as part of their treatment, which is one of the most cost-effective cancer treatments. Notably, aroundExpand
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A role for receptor tyrosine phosphataseζ in glioma cell migration
Glioblastomas (GBM) are the most frequent and malignant human brain tumor type. Typically striking in adulthood, tumor progression is rapid, relentless, and ultimately leads to the patient's deathExpand
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Tryptophan mutants of human C5a anaphylatoxin: a fluorescence anisotropy decay and energy transfer study.
Three mutants of the anaphylatoxin C5a were prepared with positions 2, 64 and 70, respectively, substituted by tryptophan. The last mutant was additionally labelled at Cys27 for fluorescence energyExpand
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Analysis of molecular determinants in native AMPA receptors
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Analysis on Homogeneous Spaces March 22-25 , 2007
s of Talks http://www.math.arizona.edu/ ̃ahs
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Biology-guided radiotherapy: Redefining the role of radiotherapy in metastatic cancer.
The emerging biological understanding of metastatic cancer and proof-of-concept clinical trials suggest that debulking all gross disease holds great promise for improving patient outcomes. However,Expand