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Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth.
BACKGROUND Preterm birth is a significant public health problem, affecting over 1 in 10 live births and contributing largely to infant mortality and morbidity. Everyday exposure to environmentalExpand
Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial.
IMPORTANCE Asthma and wheezing begin early in life, and prenatal vitamin D deficiency has been variably associated with these disorders in offspring. OBJECTIVE To determine whether prenatal vitaminExpand
Environmental phthalate exposure and preterm birth.
IMPORTANCE Preterm birth is a leading cause of neonatal mortality, with a variety of contributing causes and risk factors. Environmental exposures represent a group of understudied, but potentiallyExpand
Pregnancy disorders that lead to delivery before the 28th week of gestation: an epidemiologic approach to classification.
Epidemiologists have grouped the multiple disorders that lead to preterm delivery before the 28th week of gestation in a variety of ways. The authors sought to identify characteristics that wouldExpand
Clinical Risk Factors for Preeclampsia in the 21st Century
OBJECTIVE: We sought to validate several clinical risk factors previously described for preeclampsia in a large contemporary multicenter prospective cohort. METHODS: We enrolled women from threeExpand
Fetal bisphenol A exposure: concentration of conjugated and unconjugated bisphenol A in amniotic fluid in the second and third trimesters.
Bisphenol A (BPA) is an estrogenic compound widely used in polycarbonate plastics. The placental enzyme β-glucuronidase may deconjugate BPA into its "free" active form. We sought to quantify levelsExpand
Maternal preeclampsia predicts the development of bronchopulmonary dysplasia.
OBJECTIVE To test the hypothesis that exposure to preeclampsia is associated with an increased risk of bronchopulmonary dysplasia (BPD). STUDY DESIGN A prospective cohort study of 107 babies bornExpand
Breathing life into the lifecourse approach: pregnancy history and cardiovascular disease in women.
The lifecourse approach to epidemiology has broadened our understanding of chronic disease as a developmental process that evolves over the entire lifespan. Subclinical syndromes at an early phase inExpand
Management of Multiple Sclerosis During Pregnancy and the Reproductive Years: A Systematic Review
OBJECTIVE: To examine the evidence guiding management of multiple sclerosis (MS) in reproductive-aged women. DATA SOURCES: We conducted an electronic literature search using PubMed,Expand
Longitudinal evaluation of predictive value for preeclampsia of circulating angiogenic factors through pregnancy.
OBJECTIVE The purpose of this study was to examine whether longitudinally sampled maternal angiogenic concentrations predict preeclampsia. STUDY DESIGN Plasma sFlt-1 and placental growth factorExpand