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Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial.
ONYX-015 is an E1B-55kDa gene-deleted adenovirus engineered to selectively replicate in and lyse p53-deficient cancer cells. To evaluate the selectivity of ONYX-015 replication and cytopathic effectsExpand
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Optimizing Outcomes in Bariatric Surgery: Outpatient Laparoscopic Gastric Bypass
Background:Roux-en-Y gastric bypass (RYGB) is an effective treatment of severe obesity and one of the fastest growing surgical procedures in the United States. Methods:A single institutionExpand
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Pregnancy outcomes after gastric-bypass surgery.
BACKGROUND The purpose of this study is to compare outcomes of patients who become pregnant within the first year after surgery and those who delayed pregnancy until after 1 year after surgery. Expand
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Internal hernias after laparoscopic Roux-en-Y gastric bypass.
BACKGROUND Laparoscopic gastric bypass (Lap-RYGB) is an increasingly common procedure performed for severe obesity. Internal hernias are a potential problem associated with Lap-RYGB, and little isExpand
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Surgical management of thyroid cancer invading the airway
AbstractBackground: Locally advanced thyroid cancer invading the tracheal cartilage represents a difficult treatment dilemma during thyroidectomy. Methods: A retrospective chart review was performedExpand
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A prospective randomized trial demonstrating valved implantable ports have fewer complications and lower overall cost than nonvalved implantable ports.
BACKGROUND The purpose of the current study was to evaluate whether a totally implanted valved subcutaneous port system would have fewer complications as compared to a standard nonvalved port. Expand
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Cryosurgical ablation of hepatic tumors.
BACKGROUND Cryosurgical ablation of hepatic tumors relies on nonspecific tissue necrosis due to freezing as well as microvascular thrombosis. Patients with selected primary and metastatic hepaticExpand
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Radiation safety with breast sentinel node biopsy.
BACKGROUND Sentinel lymph node biopsy with Technetium 99m sulfur colloid (Tc99m) is an evolving technique that offers the potential for improved staging of breast cancer with decreased morbidity.Expand
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Laparoscopic Roux-en-Y gastric bypass in morbidly obese and super morbidly obese patients.
BACKGROUND Our objective was to compare the outcomes after laparoscopic Roux-en-Y gastric bypass (RYGB) in morbidly obese (body mass index [BMI] <50) patients with super morbidly obese (BMI >50)Expand
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Routine ilioinguinal nerve excision in inguinal hernia repairs.
BACKGROUND Chronic inguinal neuralgia is one of the most significant complications following inguinal hernia repair. Routine ilioinguinal nerve excision has been proposed as a means to avoid thisExpand
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