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alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 1. Survey of natural pigments with potent inhibitory activity.
SoA and YGM extracts gave more potent maltase inhibitory activities than those of the free AGH assay, with IC(50) values of 0.17 and 0.26 mg/mL, respectively, indicating that anthocyanins would have a potential function to suppress the increase in postprandial glucose level from starch. Expand
The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation.
In mice, VPY treatment reduced DSS-induced colitis symptoms and weight loss, improved colon histology, reduced MPO activity, and decreased gene expression of the pro-inflammatory cytokines TNF-α, IL-6,IL-1β, IFN-γ and IL-17 in the colon. Expand
In Vitro Survey of α-Glucosidase Inhibitory Food Components
A survey of food components with α-glucosidase (AGH) inhibitory activity was conducted to identify a prophylactic effect for diabetes in food. Sardine muscle hydrolyzed by alkaline protease showedExpand
Gastrointestinal enzyme production of bioactive peptides from royal jelly protein and their antihypertensive ability in SHR.
The gastrointestinal enzyme production of antihypertensive peptides from RJ was reported here to clarify the potential physiological function of royal jelly and to find a good resource of ACE inhibitory peptides produced by the gastrointestinal enzyme hydrolyses. Expand
Inhibitory Effect of α-Glucosidase Inhibitors Varies According to Its Origin
The magnitude of AGH inhibition was greatly affected by its origin, and more attention relating to AGH origin would be needed to evaluate in vitro AGH inhibitory effect. Expand
Preparation and characterization of novel bioactive peptides responsible for angiotensin I‐converting enzyme inhibition from wheat germ
Judging from the high content and powerful ACE inhibitory activity, Ile‐Val‐Tyr was identified as a main contributor to the ACE inhibition of the hydrolyzate and 16 peptides with the IC50 value of less than 20 μm were identified from the WG hydrolyZate. Expand
α-Glucosidase Inhibitory Action of Natural Acylated Anthocyanins. 2. α-Glucosidase Inhibition by Isolated Acylated Anthocyanins
Four diacylated pelargonidin (Pg:  SOA-4 and SOA-6), cyanidin (Cy:  YGM-3), and peonidin (Pn:  YGM-6) 3-sophoroside-5-glucosides isolated from the red flowers of the morning glory, Pharbitis nil cv.Expand
Latent production of angiotensin I‐converting enzyme inhibitors from buckwheat protein
BW proteins offer a potential resource for producing ACE inhibitory peptides during the digestion process, and a single oral administration of BW digest lowered the systolic blood pressure of a spontaneously hypertensive rat. Expand
The 10trans,12cis isomer of conjugated linoleic acid suppresses the development of hypertension in Otsuka Long-Evans Tokushima fatty rats.
It is speculated that the antihypertensive effect of 10t,12c-CLA can be attributed to the lowered secretion of hypertensive adipocytokines from abdominal adipose tissues. Expand
Production of new antioxidant compound from mycosporine-like amino acid, porphyra-334 by heat treatment.
Abstract In this study, we evaluated the antioxidant activity (diphenylpicrylhydrazyl (DPPH)-radical scavenging activity) of the low-molecular weight fraction of water-soluble Susabinori ( PorphyraExpand