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Progressive graft fibrosis and donor-specific human leukocyte antigen antibodies in pediatric late liver allografts.
- A. Miyagawa-Hayashino, A. Yoshizawa, +7 authors H. Haga
- Liver transplantation : official publication of…
- 1 November 2012
The role of donor-specific anti-human leukocyte antigen antibodies (DSAs) that develop late after living donor liver transplantation is unknown. Seventy-nine pediatric recipients who had good graft… Expand
Significance of C4d staining in ABO-identical/compatible liver transplantation
Complement degradation product C4d has become an important marker of humoral or antibody-mediated rejection in renal and heart allograft biopsies. Although there have been several reports on the… Expand
The Bcr-Abl Kinase Inhibitor INNO-406 Induces Autophagy and Different Modes of Cell Death Execution in Bcr-Abl-Positive Leukemias.
The blockade of Bcr-Abl signaling suppresses cellular growth and induces cell death in Bcr-Abl + cells. While they are known to promote caspase-mediated apoptosis, it remains unclear whether… Expand
CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis
- H. Hirai, T. Fujishita, +7 authors M. Taketo
- Medicine, Biology
- Clinical & Experimental Metastasis
- 18 October 2014
To understand colon cancer metastasis, we earlier analyzed a mouse model that developed liver metastasis of cancer cells disseminated from the spleen. We suggested that CCR1+ bone marrow (BM)-derived… Expand
Human interleukin‐9 supports formation of a subpopulation of erythroid bursts that are responsive to interleukin‐3
- Y. Sonoda, T. Maekawa, Y. Kuzuyama, T. Abe, Steven C. Clark
- Biology, Medicine
- American journal of hematology
- 1 October 1992
We have investigated the biological activities of recombinant human interleukin‐9 (IL‐9) on enriched hematopoietic progenitors, alone or in combination with other cytokines, including Epo, G‐CSF,… Expand
Isolation of mesenchymal stromal/stem cells from small-volume umbilical cord blood units that do not qualify for the banking system
- S. Yoshioka, Y. Miura, +10 authors T. Maekawa
- International Journal of Hematology
- 30 June 2015
The clinical application of mesenchymal stromal/stem cells (MSCs) has been extensively explored. In this study, we examined the availability of freshly donated umbilical cord blood (UCB) units that… Expand
Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population.
- C. Terao, H. Yoshifuji, +29 authors F. Matsuda
- Biology, Medicine
- American journal of human genetics
- 8 August 2013
Takayasu arteritis (TAK) is an autoimmune systemic vasculitis of unknown etiology. Although previous studies have revealed that HLA-B*52:01 has an effect on TAK susceptibility, no other genetic… Expand
A novel tumor-related protein, C7orf24, identified by proteome differential display of bladder urothelial carcinoma.
- S. Kageyama, H. Iwaki, +9 authors T. Yoshiki
- Biology, Medicine
- Proteomics. Clinical applications
- 1 February 2007
Proteome analysis of bladder cancer with narrow-range pH 2-DE has identified a novel protein on chromosome 7 encoded by ORF 24 (C7orf24) as one of the highly expressed proteins in cancer cells.… Expand
Actions of human interleukin-4/B-cell stimulatory factor-1 on proliferation and differentiation of enriched hematopoietic progenitor cells in culture
We studied the effects of recombinant human interleukin-4 (IL-4) on colony formation by enriched hematopoietic progenitors. IL-4 alone did not support colony formation at all. When IL-4 was combined… Expand
CCAAT/enhancer-binding protein β expressed by bone marrow mesenchymal stromal cells regulates early B-cell lymphopoiesis.
The transcription factor CCAAT/enhancer-binding protein β (C/EBPβ) regulates the differentiation of a variety of cell types. Here, the role of C/EBPβ expressed by bone marrow mesenchymal stromal… Expand