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Long noncoding RNA MALAT1 associates with the malignant status and poor prognosis in glioma
The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a bona fide long noncoding RNA (lncRNA). LncRNA MALAT1 was discovered as a prognostic factor for lung cancer metastasis but also… Expand
miR-21 as an independent biochemical recurrence predictor and potential therapeutic target for prostate cancer.
PURPOSE Abnormal miRNA expression is associated with prostate cancer progression. However, the relationship between miRNA and biochemical recurrence after radical prostatectomy is not well… Expand
Correlation of hedgehog signal activation with chemoradiotherapy sensitivity and survival in esophageal squamous cell carcinomas.
OBJECTIVE To investigate the significance of hedgehog signaling pathway in chemoradiotherapy sensitivity and its effect on the prognosis of esophageal squamous cell carcinoma. METHODS In the… Expand
Mechanically expanding the zona pellucida of human frozen thawed embryos: a new method of assisted hatching.
OBJECTIVE To determine whether a new assisted hatching (AH) method increases the implantation and clinical pregnancy rates of frozen-thawed day-3 (D3) embryos. DESIGN Prospective study. SETTING A… Expand
Reduced Expression of PER3 Is Associated with Incidence and Development of Colon Cancer
- Xiaoliang Wang, Dongwang Yan, +10 authors Z. Peng
- Annals of Surgical Oncology
- 17 February 2012
BackgroundPeriod 3 (PER3), a circadian regulation protein, influences cell cycle, growth, and differentiation. The aim of the present study was to determine whether PER3 expression is associated with… Expand
UHRF1 overexpression is involved in cell proliferation and biochemical recurrence in prostate cancer after radical prostatectomy
- Xuechao Wan, S. Yang, +6 authors Y. Li
- Medicine, Biology
- Journal of experimental & clinical cancer…
- 17 February 2016
BackgroundBiochemical recurrence (BCR) is widely used to define the treatment success and to make decisions on if or how to initiate a secondary therapy, but uniform criteria to define BCR after… Expand
Insufficient histone-3 lysine-9 deacetylation in human oocytes matured in vitro is associated with aberrant meiosis.
OBJECTIVE To characterize histone acetylation during meiosis in human oocytes matured in vitro or in vivo. DESIGN Experimental study. SETTING University reproductive medical center. PATIENT(S)… Expand
Correlation between ficolin-3 and vascular endothelial growth factor-to-pigment epithelium-derived factor ratio in the vitreous of eyes with proliferative diabetic retinopathy.
- B. Zheng, T. Li, H. Chen, X. Xu, Zhi’an Zheng
- American journal of ophthalmology
- 1 December 2011
PURPOSE To investigate the relationship of ficolin-3 with inflammatory and angiogenic factors, namely, vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF), in the… Expand
Suppression of BCRP expression and restoration of sensitivity to chemotherapy in multidrug-resistant HCC cell line HEPG2/ADM by RNA interference.
BACKGROUND/AIMS Breast cancer resistance protein (BCRP) is an ATP-binding cassette multidrug transporter that confers resistance to various anticancer drugs like Adriamycin. Overexpression of BCRP… Expand
Dynamic and direct pathogen load surveillance to monitor disease progression and therapeutic efficacy in central nervous system infection using a novel semi-quantitive sequencing platform.
Abstract We reported a cluster of meningitis cases where next-generation sequencing enabled comprehensive and rapid diagnosis of causative agents. Study attempted a novel application of… Expand