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Identification of Ligands for DAF-12 that Govern Dauer Formation and Reproduction in C. elegans
In response to environmental and dietary cues, the C. elegans orphan nuclear receptor, DAF-12, regulates dauer diapause, reproductive development, fat metabolism, and life span. Despite strongExpand
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Chronic low-level mercury exposure, BDNF polymorphism, and associations with cognitive and motor function.
Potential cognitive and motor effects from exposure to elemental mercury (Hg(0)) were examined in the presence and absence of a polymorphism (Val66Met) in brain-derived neurotrophic factor (BDNF). AExpand
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Multi-level Anomaly Detection in Industrial Control Systems via Package Signatures and LSTM Networks
TLDR
We outline an anomaly detection method for industrial control systems (ICS) that combines the analysis of network package contents that are transacted between ICS nodes and their time-series structure. Expand
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The association between a genetic polymorphism of coproporphyrinogen oxidase, dental mercury exposure and neurobehavioral response in humans.
We previously described a polymorphism in exon 4 of the gene encoding the heme biosynthetic pathway enzyme, coproporphyrinogen oxidase (CPOX4), which significantly modifies the effect of mercuryExpand
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LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.
Although widely prescribed for their potent antiinflammatory actions, glucocorticoid drugs (e.g., dexamethasone) cause undesirable side effects that are features of the metabolic syndrome, includingExpand
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Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors
Objective Somatostatin receptors (SSTRs), products of gene superfamily SSTR1-5, are commonly expressed in neuroendocrine tumors (NETs). Somatostatin analogs (SSAs) bind to SSTRs and are used asExpand
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MicroRNA‐195‐5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression
It has been reported that expression of glucose transporter member 3 (GLUT3) is up‐regulated in bladder cancers. However, the regulating mechanism remains unknown. Here, we assessed whether microRNAsExpand
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Particulate Matter Air Pollution and the Risk of Incident CKD and Progression to ESRD.
Elevated levels of fine particulate matter <2.5 µm in aerodynamic diameter (PM2.5) are associated with increased risk of cardiovascular outcomes and death, but their association with risk of CKD andExpand
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ASEB: a web server for KAT-specific acetylation site prediction
TLDR
Protein lysine acetylation plays an important role in the normal functioning of cells, including gene expression regulation, protein stability and metabolism regulation. Expand
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Effect of various doses of vitamin D supplementation on pregnant women with gestational diabetes mellitus: A randomized controlled trial.
It has previously been reported that the influence of vitamin D on the metabolism of calcium and phosphorus is associated with diabetes, cardiovascular disease, Alzheimer's disease, cancer and otherExpand
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