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Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging.
- R. S. Ramrattan, T. L. van der Schaft, C. Mooy, W. D. de Bruijn, P. Mulder, P. D. de Jong
- MedicineInvestigative ophthalmology & visual science
- 1 May 1994
In advanced stages of age-related macular degeneration, the decrease in choriocapillary density and diameter was significantly larger than in normal maculae, but the thickness of the choroid and Bruch's membrane was the same.
Histologic features of the early stages of age-related macular degeneration. A statistical analysis.
- T. L. van der Schaft, C. Mooy, W. D. de Bruijn, F. G. Oron, P. Mulder, P. D. de Jong
- MedicineOphthalmology
- 1 February 1992
Morphologic changes in age‐related maculopathy
- M. Kliffen, T. L. van der Schaft, C. Mooy, P. D. de Jong
- MedicineMicroscopy research and technique
- 15 January 1997
The most prominent aging changes in early stages of ARM are drusen and basal laminar deposit (BLD), both extracellular deposits, that are assumed to be important in the development of ARM.
Early stages of age-related macular degeneration: an immunofluorescence and electron microscopy study.
- T. L. van der Schaft, C. Mooy, W. D. de Bruijn, P. D. de Jong
- Medicine, BiologyThe British journal of ophthalmology
- 1 October 1993
Investigating whether immune complex depositions can be detected in maculae with early stages of age-related macular degeneration and to explain the macrophage reaction before the disciform reaction found that long spacing collagen was selectively internalised by these cells.
Increased prevalence of disciform macular degeneration after cataract extraction with implantation of an intraocular lens.
- T. L. van der Schaft, C. Mooy, W. D. de Bruijn, P. Mulder, J. Pameyer, P. D. de Jong
- MedicineThe British journal of ophthalmology
- 1 June 1994
There was no significant correlation between either age-related changes in the macula or disciform degeneration and the length of time between cataract surgery and death, and these findings do not confirm that disciform scar formation is caused by an increase in ultraviolet or blue light.
Is basal laminar deposit unique for age-related macular degeneration?
- T. L. van der Schaft, W. D. de Bruijn, C. Mooy, D. Ketelaars, P. D. de Jong
- MedicineArchives of ophthalmology
- 1991
It is thought that basal laminar deposit is similar to fibrous long-spacing collagen and thus does not seem to be a purely ocular abnormality.
Element analysis of the early stages of age-related macular degeneration.
- T. L. van der Schaft, W. D. de Bruijn, C. Mooy, D. Ketelaars, P. D. de Jong
- MedicineArchives of ophthalmology
- 1 March 1992
No relationship was found between the detection of zinc and the presence of BLD or drusen in the macula or surrounding structures in 38 postmortem human maculae investigated by electron-probe x-ray microanalysis.
Results of penetrating keratoplasty for pseudophakic bullous keratopathy with the exchange of an intraocular lens.
- T. L. van der Schaft, G. van Rij, J. Renardel de Lavalette, W. Beekhuis
- MedicineThe British journal of ophthalmology
- 1 September 1989
In patients with pseudophakic corneal oedema the authors continue to exchange the intraocular lens by a Pearce tripod posterior chamber lens sutured to the iris when it is necessary to remove the lens.