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Inhibition of nitric oxide synthase expression by PPM-18, a novel anti-inflammatory agent, in vitro and in vivo.
PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-kappaB to promoter and exerts a beneficial effect in the mouse model of sepsis and protects mice against LPS-induced lethal toxicity. Expand
Antimicrobial coatings: a remedy for medical device-related infections.
The mechanisms involved in the different approaches to antimicrobial coatings are discussed and a new application that seems to offer an antimicrobial surface that is effective for long-term medical implants and suitable for a variety of drugs is reported on. Expand
Thymic atrophy caused by ethanol in a mouse model for binge drinking: involvement of endogenous glucocorticoids.
It is suggested that a single dose of EtOH induces thymic atrophy which is predominantly mediated by increased levels of endogenous glucocorticoid levels which might have immunosuppressive effects. Expand
IRF-1-mediated CAS expression enhances interferon-gamma-induced apoptosis of HT-29 colon adenocarcinoma cells.
- M. Jiang, T. L. Lin, T. Lee, H. T. Huang, C. Lin, C. Liao
- Biology, Medicine
- Molecular cell biology research communications…
- 1 November 2001
The results indicate that tumor cells highly expressing CAS may be more susceptible to apoptosis induced by reagents that are capable of inducing CAS expression, and may be a target for the elimination of tumors. Expand
275 Up-regulation of prostatic cannabinoid receptor type 2 following capsaicin-induced prostatitis in castrated and non-castrated rats
- T. L. Lin
- 1 March 2016
EXERCISE-INDUCED NITRIC OXIDE SYNTHASE GENE EXPRESSION
Nandrolone decanoate reduces the premature mortality of cardiomyopathic hamsters.
Male hamsters of an inbred strain carrying a genetic trait for cardiomyopathy were dosed by sc injection weekly with an anabolic-androgenic steroid, nandrolone decanoate, beginning when 3 months old, and significantly prolonged survival of the hamsters. Expand