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Cholesterol-lowering therapy evokes time-limited changes in serotonergic transmission
A number of studies have reported an increased risk for violent deaths and depression in subjects with reduced serum cholesterol concentrations. Links with hypothesized impairment of serotoninExpand
Increase of adhesion molecules, fibrinogen, type‐1 plasminogen activator inhibitor and orosomucoid in growth hormone (GH) deficient adults and their modulation by recombinant human GH replacement
GH deficiency (GHD) is usually associated with a higher incidence of cardiovascular disease (CVD). The aim of this study was to establish whether patients with GHD, like those with CVD, show anExpand
Ultrasonography of the uterus within 6 weeks following Cesarean section
ObjectiveThe aim of the study was to compare the integrity of the uterine scar after elective and urgent Caesarean section (CS) and specify a technique to describe the sonographicExpand
Evaluation of von Willebrand factor with a fully magnetically levitated centrifugal continuous-flow left ventricular assist device in advanced heart failure.
BACKGROUND Contemporary continuous-flow left ventricular assist devices (CF-LVADs) are associated with degradation of von Willebrand factor (vWF) high-molecular-weight multimers (HMWMs), a criticalExpand
Detection of apoptotic cells and expression of Ki‐67 antigen, Bcl‐2, p53 oncoproteins in human parathyroid adenoma
Presence of apoptotic cells and immunoreactivity to Ki‐67, bcl‐2 and p53 were studied in 20 cases of parathyroid adenoma. To determine apoptosis, the DNA nick end labeling method was used. 85% of theExpand
Increasing plasma levels of soluble cell adhesion molecules (sE-Selectin, sP-Selectin and sICAM-1) in overweight adults with combined hyperlipidemia.
Combined hyperlipidemia (coincident present hypercholesterolemia and hypertriglyceridemia) may contribute to the development of atherosclerosis and coronary artery disease by increasing of cellExpand
Tobacco smoking strongly modifies the association of prothrombin G20210A with undetermined stroke: consecutive survivors and population-based controls.
OBJECTIVE Due to contradictory results of previous studies evaluating the association between ischemic stroke (IS) and thrombophilic polymorphisms, their routine screening in IS patients,Expand
[Guidelines of Czech Association for Thrombosis and Haemostasis of the Czech Medical Association of J. E. Purkyně for safety treatment with new oral anticoagulants (NOAC) - dabigatran etexilate,
There are presently new oral anticoagulants (NOAC) for prevention and the treatment of thromboembolic diseases and they are registered in CZ. It concerns of orally direct inhibitors of thrombinExpand
[NO (nitric oxide) and its significance in regulation of vascular homeostasis].
The endothelium is the largest autocrine and endocrine organ of the human organism. It participates in the regulation of the blood flow and tonus of the vascular wall, activation of thrombocytes,Expand
28 day post-operative persisted hypercoagulability after surgery for benign diseases: a prospective cohort study
BackgroundSurgery for benign disease is associated with a low-risk of developing venous thromboembolism (VTE). Despite a relatively low incidence of postoperative VTE in patients after electiveExpand