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Classification of acid denaturation of proteins: intermediates and unfolded states.
A systematic investigation of the effect of acid on the denaturation of some 20 monomeric proteins indicates that several different types of conformational behavior occur, depending on the protein,Expand
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Three conserved glycine residues in valine activation of gramicidin S synthetase 2 from Bacillus brevis.
The translated product from the gene fragment containing the second and third domains of gramicidin S synthetase 2 was purified to an essentially homogeneous state. It showed valine- andExpand
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[Immunologic memory].
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Molecular cloning and nucleotide sequence of the gramicidin S synthetase 1 gene.
The entire gene for gramicidin S synthetase 1 (GS 1) was cloned into the plasmid vector pUC18, and the nucleotide sequences of the GS 1 gene and its flanking region were determined. The full-lengthExpand
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Effect of single base substitutions at glycine-870 codon of gramicidin S synthetase 2 gene on proline activation.
The mutant gene coding for a proline-activating domain (grs2-pro) was cloned and sequenced from Bacillus brevis Nagano, BII-3 strain, which produces gramicidin S synthetase 2 defective inExpand
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Purification and properties of branched chain amino acid aminotransferase from gramicidin S-producing Bacillus brevis.
The branched chain amino acid aminotransferase [EC 2.6.1.42] was purified to a homogeneous state from a gramicidin S-producing strain of Bacillus brevis. The enzyme had a molecular weight of aboutExpand
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Further studies on the radioresistance of antibody producing cells: characterization of the survival curve.
An experiment was carried out to characterize the survival curve of 19S and 7S antibody producing cells exposed to suprahigh doses of radiation. The antibody producing cells were derived from spleenExpand
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Sulfhydryl groups related to the catalytic activity of gramicidin S synthetase 1 of Bacillus brevis.
Gramicidin S synthetase 1 (GS 1) [EC 5.1.1.11] (phenylalanine racemase) of Bacillus brevis contained about six sulfhydryl groups as determined by titration of the enzyme with 5,5'-dithiobisExpand
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A comparative study of sulfhydryl groups required for the catalytic activity of gramicidin S synthetase and isoleucyl tRNA synthetase.
The sulfhydryl groups required for the catalytic activity of gramicidin S synthetase of Bacillus brevis and Escherichia coli isoleucyl tRNA synthetase were compared. In gramicidin S synthetase 2(GSExpand
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