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Clinical significance of cloned expansion and CD5 down-regulation in Epstein-Barr Virus (EBV)-infected CD8+ T lymphocytes in EBV-associated hemophagocytic lymphohistiocytosis.
Epstein-Barr virus (EBV) is the pathogen that most commonly triggers infection-associated hemophagocytic lymphohistiocytosis (HLH) and ectopically infects CD8(+) T cells in EBV-associated HLHExpand
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Cre recombinase‐controlled expression of the mb‐1 allele
The mb-1 gene is located on chromosome 7 of the mouse genome and it is composed of five exons encoding Ig, which is a B cell-specific protein and an element of the B cell antigen receptor complexExpand
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A Protein Identical to the Yolk Protein Is Stored in the Testis in Male Red Sea Urchin, Pseudocentrotus depressus.
Female sea urchins store the major yolk protein (MYP) in ovarian nutritive phagocytes before vitellogenesis. Using immunological procedures, we detected MYP in the testicular nutritive phagocytes ofExpand
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Induction and clonal expansion of tumor‐specific cytotoxic T lymphocytes from renal cell carcinoma patients after stimulation with autologous dendritic cells loaded with tumor cells
Melanoma and renal cell carcinoma (RCC) are considered to be the most immunogenic tumors in humans. To generate conditions to induce primary T‐cell responses against RCC and to allow furtherExpand
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Autocrine transformation by fibroblast growth factor 9 (FGF‐9) and its possible participation in human oncogenesis
Transfection of human fibroblast growth factor 9 (FGF‐9) cDNA into mouse BALB/c 3T3 clone A31 cells led to morphological transformation of the cells and foci formation 4 weeks later. IsolatedExpand
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Immunophenotypic analysis of Epstein–Barr virus (EBV)‐infected CD8+ T cells in a patient with EBV‐associated hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is a severe and often fatal condition characterized by uncontrolled activation of T cells and macrophages. In Epstein–Barr virus (EBV)‐associated HLHExpand
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Expression and characterization of a chimeric bispecific antibody against fibrin and against urokinase-type plasminogen activator.
We have produced a chimeric bispecific antibody that has dual specificity of human fibrin and urokinase-type plasminogen activator (u-PA). Complementary DNAs for variable regions of both anti-fibrinExpand
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Monoclonal antibodies to human interferon-gamma. I. Antibodies to a synthetic carboxyl-terminal peptide.
Two types of hybridomas secreting monoclonal antibodies (MAB) against human interferon-gamma (HuIFN-gamma) were obtained by somatic cell hybridization between mouse myeloma P3U1 cells and spleenExpand
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ANAPLASTIC CARCINOMA OF THE THYROID WITH OSTEOCLAST‐LIKE GIANT CELLS
An unusual anaplastic thyroid carcinoma with osteoclast‐like giant cells is reported in a 72‐year‐old woman. Monotonous proliferation of variously sized mononuclear tumor cells interspersed withExpand
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In vitro and in vivo characterization of graft‐versus‐tumor responses in melanoma patients after allogeneic peripheral blood stem cell transplantation
It has been shown that after allogeneic peripheral blood stem cell transplantation (PBSCT), donor T cells can induce potent graft‐versus‐tumor (GVT) effects in hematologic malignancies and possiblyExpand
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