Prenatal exposure to an NMDA receptor antagonist, MK-801 reduces density of parvalbumin-immunoreactive GABAergic neurons in the medial prefrontal cortex and enhances phencyclidine-induced…
Findings suggest that prenatal blockade of NMDA receptors disrupts GABAergic neurodevelopment in medial prefrontal cortex, and that this disruption of GABAergic development may be related to the enhancement of the locomotion-inducing effect of PCP in postpubertal but not juvenile offspring.
DNA Methylation Profiles of the Brain-Derived Neurotrophic Factor (BDNF) Gene as a Potent Diagnostic Biomarker in Major Depression
Results indicate that classification based on the DNA methylation profiles of CpG I of the BDNF gene may be a valuable diagnostic biomarker for major depression.
Characteristics of Postictal Headache in Patients with Partial Epilepsy
The results suggest that migraine- like PIH is related to particular regions of epileptogenic focus and that susceptibility to migraine headache predisposes to migraine-like PIH.
Olanzapine increases plasma ghrelin level in patients with schizophrenia
Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior
These results suggest the possible involvement of the A-1438A polymorphism of the 5-HT2A receptor gene in impulsive behavior; this was evaluated using a behavioral task measure that can directly reveal the traits of human impulsivebehavior.
Reliability and validity of the Japanese version of the Liebowitz Social Anxiety Scale.
Aripiprazole augmentation to antidepressant therapy in Japanese patients with major depressive disorder: a randomized, double-blind, placebo-controlled study (ADMIRE study).
Effect of the Dopamine D1/5 Antagonist SCH 23390 on the Acquisition of Conditioned Fear
A prospective, open-label, flexible-dose study of quetiapine in the treatment of delirium.
- Y. Sasaki, T. Matsuyama, T. Koyama
- Psychology, MedicineThe Journal of clinical psychiatry
- 15 November 2003
Quetiapine may be a useful alternative to conventional neuroleptics in the treatment of delirium due to its rapid onset and relative lack of adverse events.
Different effects of a single and repeated administration of clozapine on phencyclidine-induced hyperlocomotion and glutamate releases in the rat medial prefrontal cortex at short- and long-term…
- T. Abekawa, Koki Ito, T. Koyama
- Psychology, BiologyNaunyn-Schmiedeberg's Archives of Pharmacology
- 26 April 2007
It is suggested that subchronically treated clozapine-induced long-lasting downregulation of 5-HT2A receptors may block the enhanced PCP-induced neurochemical and behavioral changes.