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Rapid Detection and Quantification of Japanese Encephalitis Virus by Real‐Time Reverse Transcription Loop‐Mediated Isothermal Amplification
The results indicate that the RT‐LAMP assay established in this study is specific for Japanese encephalitis virus, and allows more rapid detection and quantification of the virus. Expand
Seroprevalence of Coxiella burnetii infections among cats in different living environments.
- T. Komiya, K. Sadamasu, Mun-Il Kang, Sadao Tsuboshima, H. Fukushi, K. Hirai
- The Journal of veterinary medical science
- 25 September 2003
In this study, the prevalence of C. burnetii infection among cats in different living environments was found and it is difficult to deny that stray cats would be one of the important sources of infection for human Q fever. Expand
A seroepidemiological study of the risks of Q fever infection in Japanese veterinarians
It is suggested that Japanese veterinarians have a higher risk of infection by C. burnetii than other members of the Japanese population. Expand
Japanese encephalitis virus production in Vero cells with serum-free medium using a novel oscillating bioreactor.
- Hiroko Toriniwa, T. Komiya
- Biology, Medicine
- Biologicals : journal of the International…
- 1 October 2007
A novel oscillating bioreactor, BelloCell, was successfully applied for the cultivation of Vero cells using serum-free medium, and the production of Japanese encephalitis virus, with results markedly higher than with microcarrier culture. Expand
Prevalence of Coxiella burnetii antibodies in blood donors in Ankara, Central Anatolia, Turkey.
- S. Kılıç, G. Yılmaz, T. Komiya, Yasemin Kurtoğlu, E. Karakoç
- The new microbiologica
- 1 October 2008
The high rate of C. burnetii phase II antibodies among blood donors is a reflection of the high prevalence of Q fever in this area of Turkey and indicates the need for further studies, not only to determine the risk of transfusion-transmitted Q fever, but also to elucidate the epidemiology of Q Fever in Turkey. Expand
Identification of mutations that occurred on the genome of Japanese encephalitis virus during the attenuation process
The total nucleotide sequences of the genomes of two Japanese encephalitis virus (JEV) strains, the attenuated vaccine strain SA 14-14-2 and its parental virulent strain SA14, were determined by using the molecular cloning technique and provide a molecular basis for investigating attenuation mechanisms of JEV. Expand
Improvement of chronic nonspecific symptoms by long-term minocycline treatment in Japanese patients with Coxiella burnetii infection considered to have post-Q fever fatigue syndrome.
The results of an open label study in Japan suggest that minocycline administration is useful for improving chronic nonspecific symptoms considered to be post-Q fever fatigue syndrome caused by C. burnetii infection. Expand
Treatment of chronic fatigue syndrome with antibiotics: pilot study assessing the involvement of Coxiella burnetii infection.
The possibility of direct involvement of C. burnetii in the pathological state of CFS to be low is suggested, despite the C. burningetii infection rate being high in CFS patients. Expand
Long-term stability of Vero cell-derived inactivated Japanese encephalitis vaccine prepared using serum-free medium.
Results indicate that, in contrast to the current mouse brain- derived vaccine, the Vero cell-derived vaccine can be prepared using serum-free medium containing no animal-derived components, and that the vaccine can been stored at room temperature by adding stabilizers, suggesting the possibility of producing room temperature-stable vaccines. Expand
An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous…
- M. Lobigs, M. Pavy, +5 authors N. Petrovsky
- Biology, Medicine
- The Journal of general virology
- 1 June 2010
Equine immunizations against JEV with Advax-formulated vaccine similarly showed enhanced vaccine immunogenicity, confirming that the adjuvant effects of Advax are not restricted to rodent models. Expand