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Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil
Incubation of human neutrophils with a chemotactic peptide [N-formylmethionyl-leucylphenylalanine (fMLP)] gave rise to an increase in the phosphoinositide 3-kinase (PI3K) activity, phosphorylation ofExpand
The COUP-TFII variant lacking a DNA-binding domain inhibits the activation of the Cyp7a1 promoter through physical interaction with COUP-TFII.
The COUP-TFII (chicken ovalbumin upstream promoter-transcription factor II) nuclear receptor, which is composed of a DNA-binding domain and a ligand-binding domain, exerts pleiotropic effects onExpand
Evidence for involvement of a 12-residue peptide segment of the heavy chain in the neck region of smooth muscle myosin in formation of the 10S conformation.
Two synthetic peptides having amino acid sequences of the heavy chain segments in the neck region of porcine aorta smooth muscle myosin were used to study the formation of the 10S foldedExpand
Hypocholesterolemic effects of the LDL receptor gene transcriptional upregulator CP-230821.
CP-230821 is a novel, potent LDL receptor gene transcriptional upregulator which decreases total plasma cholesterol level. Interestingly, this plasma LDL decrease does not alter hepatic lipidExpand
Effect of YM‐16638, an Orally Active Leukotriene Antagonist, on Alanine Aminotransferase Activity In‐vitro and In‐vivo
YM-16638 ([[5-[[3-(4-acetyl-3-hydroxy-2-propylphenoxy) propyl]thio]-1,3,4-thiadiazol-2-yl]thio]acetic acid), an orally active leukotriene antagonist, induced a marked decrease in serum alanineExpand
Poster Presentations—Molecular and microbiology: Abstracts 95–124
The V3 region of SIV gp120 does not appear to be variable among laboratory isolates. However, we have observed considerable sequence variations in V3 in tissues of rhesus macaques that died from AIDSExpand