T. Kocher

Publications150
h-index62
Citations20,139
Highly Influential Citations1,377
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Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.
With a standard set of primers directed toward conserved regions, we have used the polymerase chain reaction to amplify homologous segments of mtDNA from more than 100 animal species, including… Expand
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Evolution of the cytochrome b gene of mammals.
With the polymerase chain reaction (PCR) and versatile primers that amplify the whole cytochrome b gene (approximately 1140 bp), we obtained 17 complete gene sequences representing three orders of… Expand
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Adaptive evolution and explosive speciation: the cichlid fish model
  • T. Kocher
  • Biology, Medicine
  • Nature Reviews Genetics
  • 1 April 2004
The cost of DNA sequencing continues to fall, which makes it feasible to develop genomic resources for new model species that are well suited for studying questions in evolutionary biology. The… Expand
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Monophyletic origin of Lake Victoria cichlid fishes suggested by mitochondrial DNA sequences
LAKE Victoria, together with its satellite lakes, harbours roughly 200 endemic forms of cichlid fishes that are classified as 'haplo-chromines'1,2 and yet the lake system is less than a million years… Expand
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Evolution of the cytochromeb gene of mammals
SummaryWith the polymerase chain reaction (PCR) and versatile primers that amplify the whole cytochromeb gene (∼ 1140 bp), we obtained 17 complete gene sequences representing three orders of hoofed… Expand
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  • 47
Structure and evolution of teleost mitochondrial control regions
We amplified and sequenced the mitochondrial control region from 23 species representing six families of teleost fish. The length of this segment is highly variable among even closely related species… Expand
  • 552
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The genomic substrate for adaptive radiation in African cichlid fish
Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great Lakes of East Africa. To understand the molecular mechanisms underlying cichlid phenotypic diversity, we… Expand
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Patterns of nucleotide composition at fourfold degenerate sites of animal mitochondrial genomes
Three statistics (%GC, GC-skew, and AT-skew) can be used to describe the overall patterns of nucleotide composition in DNA sequences. Fourfold degenerate third codon positions from 16 animal… Expand
  • 271
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Evolution of NADH dehydrogenase subunit 2 in east African cichlid fish.
The complete sequence (1047 bp) of the mitochondrially encoded ND2 gene was obtained from 31 species of cichlid fishes to investigate the evolutionary history of the species flocks of the East… Expand
  • 227
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Mitochondrial DNA sequences in single hairs from a southern African population.
Hypervariable parts of mitochondrial DNA (mtDNA) were amplified enzymatically and sequenced directly by using genomic DNA from single plucked human hairs. This method has been applied to study mtDNA… Expand
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