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Sonodynamic therapy of cancer using novel sonosensitizers.
Sonodynamic therapy (SDT) of cancer is based on preferential uptake and/or retention of a sonosensitizing drug (sonosensitizer) in tumor tissues and subsequent activation of the drug by ultrasound… Expand
Claudin-1 protein is a major factor involved in the tumorigenesis of colorectal cancer.
BACKGROUND The molecular and morphological alterations of the tight junctions in colorectal cancer (CRC) are still poorly understood. The possible involvement of claudin-1 (CL-1), one of the major… Expand
Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer.
BACKGROUND To understand the molecular and morphological alterations in the tight junction in colorectal cancer (CRC) tissues, the expression of eight tight junction proteins in normal and cancer… Expand
Sonodynamic therapy of cancer using a novel porphyrin derivative, DCPH‐P‐Na(I), which is devoid of photosensitivity
To improve the efficacy of sonodynamic therapy of cancer using photosensitizers, we developed a novel porphyrin derivative designated DCPH‐P‐Na(I) and investigated its photochemical characteristics… Expand
Expression of IGF-1 and IGF-1R and their relation to clinicopathological factors in colorectal cancer.
- Ichitarou Shiratsuchi, Y. Akagi, +7 authors K. Shirouzu
- Biology, Medicine
- Anticancer research
- 1 July 2011
BACKGROUND Expression of insulin-like growth factor-1 (IGF-1) and IGF-1 receptor (IGF-1R) has been shown to increase in colorectal cancer. We examined the correlation between expression of IGF-1 and… Expand
Intersphincteric resection for very low rectal cancer: a systematic review
Radical surgical treatment for very low rectal cancer near the anus has generally involved abdominoperineal resection. Various sphincter-saving operations have been developed for such tumors to… Expand
Increased claudin-1 protein expression contributes to tumorigenesis in ulcerative colitis-associated colorectal cancer.
BACKGROUND The molecular and morphological alterations of the tight junctions in ulcerative colitis (UC)-associated colorectal cancer are still poorly understood. The possible involvement of… Expand
Initial symptoms of acute radiation syndrome in the JCO criticality accident in Tokai-mura.
- M. Akashi, T. Hirama, +11 authors H. Tsujii
- Biology, Medicine
- Journal of radiation research
- 1 September 2001
A criticality accident occurred on September 30, 1999, at the uranium conversion plant in Tokai-mura (Tokai-village), Ibaraki Prefecture, Japan. When the criticality occurred, three workers saw a… Expand
Expression of monocarboxylate transporter (MCT)-4 in colorectal cancer and its role: MCT4 contributes to the growth of colorectal cancer with vascular endothelial growth factor.
BACKGROUND In tumor cells, monocarboxylate transporter (MCT)-4 regulates the excretion of lactate produced by glycolysis from the cell. MCT4 has also been reported to be involved in tumor growth and… Expand
Decreased expression of claudin-1 in rectal cancer: a factor for recurrence and poor prognosis.
AIM To investigate the potential involvement of claudin-1 (CL-1) in the tumorigenesis of rectal cancer by analyzing the correlation between CL-1 expression, clinicopathological factors and prognosis.… Expand