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Ipsilateral breast tumor recurrence (IBTR) after breast‐conserving treatment for early breast cancer
The clinical features of ipsilateral breast tumor recurrence after breast conserving therapy (BCT) for early stage breast cancer were analyzed from long‐term follow‐up of BCT in Japan to clarify risk factors and the impact of IBTR on development of distant metastases in this ethnic group. Expand
Novel combination of serum microRNA for detecting breast cancer in the early stage
A combination of five miRNA was found to be able to detect breast cancer, and this combination had a sensitivity of 97.3%, specificity of 82.9% and accuracy of 89.7% in the test cohort. Expand
Neoadjuvant anastrozole versus tamoxifen in patients receiving goserelin for premenopausal breast cancer (STAGE): a double-blind, randomised phase 3 trial.
Given its favourable risk-benefit profile, the combination of anastrozole plus goserelin could represent an alternative neoadjuvant treatment option for premenopausal women with early-stage breast cancer. Expand
Pancreatic ductal adenocarcinoma: preoperative assessment with helical CT versus dynamic MR imaging.
Dynamic MR imaging may be better than helical CT in the preoperative detection and evaluation of local tumor extension and of vascular involvement of pancreatic ductal adenocarcinomas. Expand
Neoadjuvant chemotherapy in breast cancer: prediction of pathologic response with PET/CT and dynamic contrast-enhanced MR imaging--prospective assessment.
To clarify whether fluorine 18 ((18)F) fluorodeoxyglucose (FDG) positron emission tomography (PET) and dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging performed after two cycles of neoadjuvant chemotherapy (NAC) can be used to predict pathologic response in breast cancer, a large number of women with histologically proved breast cancer were examined. Expand
Metaplastic carcinoma of the breast.
The results of this study clearly demonstrated that metaplastic carcinoma is more aggressive than invasive ductal carcinoma or invasive lobular carcinoma. Expand
Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer
- M. Ono, H. Tsuda, +12 authors Y. Fujiwara
- Biology, Medicine
- Breast Cancer Research and Treatment
- 1 April 2012
The degree of TIL correlated with immune response appear to play a substantial role in the response to NAC in TNBC, and Expression of basal markers and p53, histological grade 3, high TIL scores, and apoptosis were more frequent in T NBC and the HR−/her2+ subtype than in the HR+/HER2− subtype. Expand
FcγR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer.
- K. Tamura, C. Shimizu, +10 authors Y. Fujiwara
- Annals of oncology : official journal of the…
- 1 June 2011
The FcγR2A-131 H/H polymorphism predicted the pathological response to trastuzumab-based neoadjuvant chemotherapy in early-stage breast cancer, and the objective response in metastatic breast cancer. Expand
Evaluation of the Clinical Utility of the ICG Fluorescence Method Compared with the Radioisotope Method for Sentinel Lymph Node Biopsy in Breast Cancer
The ICG fluorescence method may be an acceptable alternative to SLN detection using RI in breast cancer, and the combination of both methods achieved a significant improvement compared with RI alone. Expand
Paclitaxel-induced peripheral neuropathy in patients receiving adjuvant chemotherapy for breast cancer
- Y. Tanabe, K. Hashimoto, +9 authors Y. Fujiwara
- International Journal of Clinical Oncology
- 1 February 2013
PIPN persists longer in older patients and in those who experience severe neuropathy, which is significantly associated with PIPN duration, as well as in patients who receive adjuvant chemotherapy for breast cancer. Expand