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- Publications
- Influence
Novel mutations of the MET proto-oncogene in papillary renal carcinomas
- Laura Schmidt, K. Junker, +16 authors B. Zbar
- Biology, Medicine
- Oncogene
- 8 April 1999
Hereditary papillary renal carcinoma (HPRC) is characterized by multiple, bilateral papillary renal carcinomas. Previously, we demonstrated missense mutations in the tyrosine kinase domain of the MET… Expand
Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus isolates.
- R. Buckheit, M. Snow, +5 authors S. Yang
- Biology, Medicine
- Antimicrobial agents and chemotherapy
- 1 April 1997
The structure-activity relationships of a series of compounds related to the nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) oxathiin carboxanilide have been described (R. W. Buckheit,… Expand
Unique Anti-Human Immunodeficiency Virus Activities of the Nonnucleoside Reverse Transcriptase Inhibitors Calanolide A, Costatolide, and Dihydrocostatolide
- R. Buckheit, E. White, +6 authors J. Bader
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 August 1999
ABSTRACT (+)-Calanolide A (NSC 650886) has previously been reported to be a unique and specific nonnucleoside inhibitor of the reverse transcriptase (RT) of human immunodeficiency virus (HIV) type 1… Expand
Structure-activity and cross-resistance evaluations of a series of human immunodeficiency virus type-1-specific compounds related to oxathiin carboxanilide.
- R. Buckheit, T. Kinjerski, +7 authors R. J. Schultz
- Biology, Medicine
- Antimicrobial agents and chemotherapy
- 1 December 1995
A series of compounds related to the nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) oxathiin carboxanilide (UC84) were evaluated for activity against the human immunodeficiency virus… Expand
The role of genotypic heterogeneity in wild type virus populations on the selection of nonnucleoside reverse transcriptase inhibitor-resistant viruses.
- T. Kinjerski, R. Buckheit
- Biology, Medicine
- Antiviral research
- 1997
Virus populations were selected in cell culture using two widely used protocols in order to evaluate the role of selection methodology on the genotype and phenotype of nonnucleoside reverse… Expand
Isolation and Characterization of HIV-1 Isolates Resistant to Oxathiin Carboxanilide Analogues: Evaluation of Variables in the Drug Resistance Selection Process
- T. Kinjerski, L. Pallansch, R. W. Buckheit
- Biology
- 1 October 1996
Virus isolates resistant to a variety of structural analogues of oxathiin carboxanilide (UC84) were selected in cell culture and phenotypically and mo!ecularly characterized in order to evaluate the… Expand
Molecular evidence of bone marrow involvement in advanced case ot Tgammadelta lymphoma with secondary myelofibrosis.
- G. Weirich, M. Sandherr, +6 authors H. Hoefler
- Medicine
- Human pathology
- 1998
We describe the case of a middle-aged man with long indolent course of generalized Tgammadelta lymphoma. The onset of secondary myelofibrosis made cytological monitoring of the bone marrow… Expand