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Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone‐induced Parkinson's disease models
- H. Takeuchi, T. Yanagida, +13 authors S. Shimohama
- Chemistry, Medicine
- Journal of neuroscience research
- 1 February 2009
Parkinson's disease (PD) is the second most common neurodegenerative disease and is characterized by dopaminergic (DA) neuronal cell loss in the substantia nigra. Although the entire pathogenesis of… Expand
Idiopathic normal pressure hydrocephalus has a different cerebrospinal fluid biomarker profile from Alzheimer's disease.
- N. Jingami, Megumi Asada-Utsugi, +8 authors A. Kinoshita
- Journal of Alzheimer's disease : JAD
The diagnosis of idiopathic normal pressure hydrocephalus (iNPH) is sometimes complicated by concomitant Alzheimer's disease (AD) pathology. The purpose of the present study is to identify an… Expand
Nonhypotensive Dose of Telmisartan Attenuates Cognitive Impairment Partially Due to Peroxisome Proliferator-Activated Receptor-&ggr; Activation in Mice With Chronic Cerebral Hypoperfusion
Background and Purpose— The effect of telmisartan, an angiotensin II Type 1 receptor blocker with peroxisome proliferator-activated receptor-&ggr;-modulating activity, was investigated against… Expand
Apolipoprotein J/Clusterin Is Induced in Vascular Smooth Muscle Cells After Vascular Injury
Background—Understanding the precise molecular mechanisms underlying the phenomenon of restenosis after PTCA may help us to develop a new strategy for the treatment of restenosis after PTCA. The… Expand
Impairment of the cortical GABAergic inhibitory system in catatonic stupor: a case report with neuroimaging.
- K. Iseki, A. Ikeda, +6 authors H. Shibasaki
- Psychology, Medicine
- Epileptic disorders : international epilepsy…
- 1 June 2009
We report the case of a 32-year-old patient who presented with catatonic stupor during the course of acute aseptic encephalitis involving the right frontotemporal area. Flumazenil-PET performed… Expand
Computed tomographic appearance of urachal carcinoma associated with urachal diverticulum misdiagnosed by cystoscopy
Urachal carcinoma associated with the urachal diverticulum is rare. We present a surgical case of this condition that was initially diagnosed as bladder urothelial carcinoma by cystoscopy, but was… Expand
Identification and functional characterization of novel mutations including frameshift mutation in exon 4 of CSF1R in patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented…
ObjectiveAdult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is caused by mutations in CSF1R. Pathogenic mutations in exons 12–22 including coding sequence of the tyrosine… Expand
Transitional cell carcinoma of the bladder associated with Crohn's disease: case report and review of the literature.
Transitional cell carcinoma of the bladder rarely occurs within the first two decades of life. We report a case of transitional cell cancer of the bladder complicating Crohn's disease and review the… Expand
A new criterion proposed for the diagnosis of hand-arm vibration syndrome.
To propose a new criterion for the diagnosis of hand-arm vibration syndrome (HAVS), we evaluated the severity of the patients in comparison with the criterion of the Ministry of Labour in Japan (MLJ)… Expand
各種の台木がウンシュウミカンの極早生系統 '山川早生' の生育および果実品質に及ぼす影響
The performance of very early ripening satsuma mandarin (C. unshiu Marc.) 'Yamakawa' grafted on 7 different rootstocks in 1988 was examined from 1994 to 1998. The growth of the scion grafted on… Expand