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Metabolism of 2,4-dinitrotoluene and 2,6-dinitrotoluene, and their dinitrobenzyl alcohols and dinitrobenzaldehydes by Wistar and Sprague-Dawley rat liver microsomal and cytosol fractions.
It was concluded that the dinitrobenzaldehydes (2,4-DNBAl and 2,6-D NBAl) were intermediates in the oxidations of dinitRObenzyl alchols and d initrobenzoic acids of male Wistar and male Sprague-Dawley (S.D.) rat livers.
Metabolism of 2,6-dinitrotoluene in male Wistar rat.
1. Unchanged 2,6-dinitrotoluene (2,6-DNT), 2-amino-6-nitrotoluene, 2,6-dinitrobenzyl alcohol, 2-amino-6-nitrobenzyl alcohol, conjugated 2,6-dinitrobenzyl alcohol and conjugated 2-amino-6-nitrobenzyl
Metabolism of 2,4-dinitrotoluene, 2,4-dinitrobenzyl alcohol and 2,4-dinitrobenzaldehyde by rat liver microsomal and cytosol fractions.
The results indicate that 2, 4-DNAl is an intermediate in the oxidation of 2, 5-DNT and suggests that the microsomal cytochrome P-450 and alcohol dehydrogenase may play an important role in the metabolic activation of 2- 4-D NT.
TH-AB-201-01: A Feasibility Study of Independent Dose Verification for CyberKnife.
The independent dose calculation for CyberKnife shows -3.0±4.2% (Mean±2SD) and the confidence limit was achieved within 5% of the tolerance level from AAPM task group 114 for non-IMRT treatment, suggesting it may be feasible to use independent dose verification for Cyber Knife treatment as the secondary check.