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Clearance of HCV Improves Insulin Resistance, Beta-Cell Function, and Hepatic Expression of Insulin Receptor Substrate 1 and 2
It was shown that clearance of HCV improves insulin resistance, beta-cell function, and hepatic IRS1/2 expression, as well as homeostasis model assessment method assessment method. Expand
Expression of cyclooxygenase‐2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation
The present study is the first to demonstrate a high expression of COX‐2 in well‐differentiated HCC and a low expression in advanced HCC, in contrast to its continuous expression during colorectal carcinogenesis. Expand
Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.
HCV infection changes a subset of hepatic molecules regulating glucose metabolism, and a possible mechanism is that HCV core-induced SOCS3 promotes proteosomal degradation of IRS1 and IRS2 through ubiquitination. Expand
Aerobic vs. resistance exercise in non-alcoholic fatty liver disease: A systematic review.
Resistance exercise may be more feasible than aerobic exercise for NAFLD patients with poor cardiorespiratory fitness or for those who cannot tolerate or participate in aerobic exercise. Expand
Vascular endothelial growth factor in patients with rheumatoid arthritis.
Serum concentration of VEGF was examined in patients with RA, osteoarthritis, systemic lupus erythematosus, SLE, systemic sclerosis and control subjects to suggest that V EGF is involved in the pathogenesis of RA and that measurement of serum concentration ofVEGF is a noninvasive, useful method for monitoring the disease activity of RA. Expand
Branched‐chain amino acids as pharmacological nutrients in chronic liver disease
Accumulating experimental evidence suggests that the favorable effects of BCAA supplementation on prognosis may be supported by unforeseen pharmacological actions of BCAAs, and the possible effects of B CAAs on albumin synthesis and insulin resistance are summarized. Expand
Insulin resistance and chronic liver disease.
Increased insulin resistance is frequently associated with chronic liver disease and is a pathophysiological feature of hepatogenous diabetes. Distinctive factors including hepatic parenchymal cellExpand
Nutritional management contributes to improvement in minimal hepatic encephalopathy and quality of life in patients with liver cirrhosis: A preliminary, prospective, open‐label study
A preliminary study to investigate the proportion of positive MHE and the effects of nutritional management on MHE finds that patients with MHE are more likely to develop overt hepatic encephalopathy. Expand
Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease.
It was found that there was a gender difference in chronic viral liver disease-related insulin resistance and a BCAA-enriched supplement improved insulin Resistance and beta cell function in male patients with chronic viral Liver disease. Expand
HBV and HCV infection in Japanese dental care workers.
Immunized workers were more protected against HBV infection than non-immunized workers, indicating that HBV vaccine was a useful measure for protection against the infection. Expand