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Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer.
PURPOSE The small GTP-binding protein Rho and its best-characterized downstream effector Rho-associated serine-threonine protein kinase, ROCK, participate in actin cytoskeleton organization, and areExpand
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Overexpression of RhoA, Rac1, and Cdc42 GTPases Is Associated with Progression in Testicular Cancer
The Rho family of GTPases are involved in actin cytoskeleton organization and associated with carcinogenesis and progression of human cancers. We investigated the roles of Rho family GTPases,Expand
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Combination of a cholinergic drug and an α‐blocker is more effective than monotherapy for the treatment of voiding difficulty in patients with underactive detrusor
Aim:  The aim of the present study was to compare the effectiveness of a cholinergic drug, an α‐blocker and combinations of the two for the treatment of underactive detrusor.
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The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia.
The aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-induced contraction of normal human bladder and detrusor overactivity associated with benign prostaticExpand
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Urodynamic effects of silodosin, a new α1A‐adrenoceptor selective antagonist, for the treatment of benign prostatic hyperplasia
To investigate urodynamically the effects of silodosin, a new α1A‐adrenoceptor‐selective antagonist, in the treatment of benign prostatic hyperplasia (BPH).
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High expression of Ran GTPase is associated with local invasion and metastasis of human clear cell renal cell carcinoma
The Ran small GTPase (Ran) is involved in the regulation of nuclear transport, microtubule nucleation and dynamics, and spindle assembly. To address the question of whether Ran protein is associatedExpand
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Increased expression of system large amino acid transporter (LAT)-1 mRNA is associated with invasive potential and unfavorable prognosis of human clear cell renal cell carcinoma
BackgroundThe system L amino acid transporter (LAT) has an important role in the transport of various amino acids, and there have been reports about the relation of this system to cancer. AlthoughExpand
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Increased interferon alpha receptor 2 mRNA levels is associated with renal cell carcinoma metastasis
BackgroundInterferon-α (IFN-α) is one of the central agents in immunotherapy for renal cell carcinoma (RCC) and binds to the IFN-α receptor (IFNAR). We investigated the role of IFNAR in RCC.MethodsWeExpand
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Renal Metanephric Adenoma Mimicking Papillary Renal Cell Carcinoma on Computed Tomography: A Case Report
We present a case of renal metanephric adenoma (MA) mimicking papillary renal cell carcinoma (PRCC) on computed tomography (CT). In the present case, double-phase enhanced CT showed a hypovascularExpand
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Maintenance monotherapy with gemcitabine after standard platinum‐based chemotherapy in patients with advanced urothelial cancer
To investigate the outcomes of gemcitabine maintenance monotherapy treatment for metastatic urothelial cancer.
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