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Porphyrins in photodynamic therapy - a search for ideal photosensitizers.
The utility of light as a therapeutic agent can be traced back over thousands of years when it was used in Ancient Egypt, India and China to treat a variety of skin diseases like psoriasis, vitiligo,Expand
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In vitro demonstration of apoptosis mediated photodynamic activity and NIR nucleus imaging through a novel porphyrin.
We synthesized a novel water-soluble porphyrin THPP and its metalated derivative Zn-THPP having excellent triplet excited state quantum yields and singlet oxygen generation efficiency. When comparedExpand
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Meso-tetrakis(p-sulfonatophenyl)N-confused porphyrin tetrasodium salt: a potential sensitizer for photodynamic therapy.
A water-soluble derivative of N-confused porphyrin (NCP) was synthesized, and the photodynamic therapeutic (PDT) application was investigated by photophysical and in vitro studies. High singletExpand
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Core-modified expanded porphyrins with large third-order nonlinear optical response.
The third-order nonlinear optical response through measurement of two-photon absorption cross-sections (TPACS) for aromatic core-modified expanded porphyrin analogues by a femtosecond open apertureExpand
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Figure-eight aromatic core-modified octaphyrins with six meso links: syntheses and structural characterization.
The synthesis and structural characterization of the first examples of aromatic core-modified figure-eight octaphyrins with six meso links and their formation with and without acid catalysts areExpand
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Short-chain basket handle porphyrins: synthesis and characterisation
Basket handle porphyrins containing short p- or m-phenylenedimethylenedioxy chains covalently linked at the ortho position of phenyl groups of 5,10,15,20-tetraphenylporphyrin have been synthesised.Expand
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Core-modified expanded porphyrins: new generation organic materials.
Even though the first expanded porphyrin was reported in the mid-1960s, the advances in its chemistry are more recent. New and powerful synthetic methods have facilitated the availability inExpand
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An ENDOR study of the tyrosyl free radical in ribonucleotide reductase from Escherichia coli
Tyrosyl radicals have been identified as components of several proteins whose function is redox chemistry. Ribonucleotide reductase is representative of this class of enzymes as its B2 subunitExpand
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Structural diversity in expanded porphyrins.
Inspired by the chemistry of porphyrins, in the last decade, a new research area where porphyrin analogues such as expanded, isomeric, and contracted porphyrins have been synthesized, and theirExpand
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Smaragdyrins: emeralds of expanded porphyrin family.
Porphyrins are tetrapyrrolic 18 π electron conjugated macrocycles with wide applications that range from materials to medicine. Expanded porphyrins, synthetic analogues of porphyrins that containExpand
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