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The neutral theory of molecular evolution.
- T. Jukes
- 1 March 2000
It is stated that these sequences differed in the cytochromes c of various species to an extent that seemed unnecessary from the standpoint of their function.
Recent evidence for evolution of the genetic code.
It is proposed that the changes are typically preceded by loss of a codon from all coding sequences in an organism or organelle, often as a result of directional mutation pressure, accompanied by Loss of the tRNA that translates the codon.
NonDarwinian evolution of protein and DNA, comparing expectations of evolution models for protein and amino acid changes
Evolutionary nucleotide replacements in DNA
Nine types of change are found in comparisons of genes from the viruses ΦX74 and G4, and they are discussed in the light of the significance of nucleotide changes in molecular evolution.
Rates of transition and transversion in coding sequences since the human-rodent divergence.
The amino acid exchange rejected least often during evolution is Asp/Glu, which is fixed at 30% the rate of transversions in silent sites, and the most mutable amino acids in this survey are threonine and serine; serinecoded by AGY is more mutable than serine coded by TCN.
Evolution of the genetic code as affected by anticodon content.
Transitions, transversions, and the molecular evolutionary clock
- T. Jukes
- BiologyJournal of Molecular Evolution
No indication was found that transversions usually originate from multiple substitutions in transitions, which could possibly be caused by mutator genes, favoring either transitions or, conversely, transversions, during DNA replication.