• Publications
  • Influence
Liver Transplantation for Familial Amyloidotic Polyneuropathy (FAP): A Single‐Center Experience Over 16 Years
TLDR
To optimize the posttransplant prognosis, LTx should be performed in the early stages of the disease, and close post‐LTx monitoring of heart function by echocardiography and of heart arrhythmia by Holter ECG is mandatory. Expand
The Kampo medicine, Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen
TLDR
The Kampo medicine, Goshajinkigan, is useful in preventing neuropathy in non-resectable or recurrent colorectal cancer patients treated with a FOLFOX regimen and there were no differences in adverse effects except for peripheral neuropathy and influence on tumor response. Expand
Programmed cell death protein 1 expression is an independent prognostic factor in gastric cancer after curative resection
TLDR
PD-1 expression is associated with a poor prognosis and is correlated with PD-L1 and Foxp3 expression in patients with gastric cancer. Expand
Comparison of long-term prognosis of laparoscopy-assisted gastrectomy and conventional open gastrectomy with special reference to D2 lymph node dissection
TLDR
LAG with D1, D1+ lymph node dissection for EGC is safe and equivalent to open gastrectomy in curability and comparable to OG with D2 lymph nodes dissection with regard to short- and long-term results. Expand
Cyclopamine decreased the expression of Sonic Hedgehog and its downstream genes in colon cancer stem cells.
TLDR
Overall, these findings show that cyclopamine treatment could down-regulate the expression of stemness markers, shh downstream genes and EMT markers on HCT-116 spheres. Expand
Sonic hedgehog relates to colorectal carcinogenesis
TLDR
This result indicates that Shh-related carcinogenesis and Shh expression may be a trigger for the adenoma-carcinoma sequence in the colon and rectum, and suggests a potential therapeutic target of hedgehog blockade in carcinogenesis. Expand
Irinotecan injures tight junction and causes bacterial translocation in rat.
TLDR
Irinotecan causes disorders in the intestinal epithelial barrier and induces bacterial translocation in rats and injures claudin-1 and occludin. Expand
Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC
TLDR
Myo1b is functionally involved in lymph node metastasis of human HNSCC through enhanced cancer cell motility and is an attractive target for new diagnostic and therapeutic strategies for patients with H NSCC. Expand
The effects of the Kampo medicine (Japanese herbal medicine) “Daikenchuto” on the surgical inflammatory response following laparoscopic colorectal resection
TLDR
Postoperative DKT administration significantly suppressed the CRP level and shortened the time until first flatus and significantly suppressed postoperative inflammation following surgery for colorectal cancer. Expand
Expression of thrombospondin-1 and Ski are prognostic factors in advanced gastric cancer
TLDR
This study shows that TSP-1 enhances angiogenesis due to its positive correlation with VEGF and MVD, and is a good prognostic factor for survival in advanced gastric cancer. Expand
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