T. Itoh

Publications175
h-index40
Citations4,796
Highly Influential Citations82
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Physiological features of visceral smooth muscle cells, with special reference to receptors and ion channels.
TLDR
The features of ion channels in vascular tissues only recently are reviewed, since this article makes only limited reference to vascular smooth muscle research. Expand
Membrane hyperpolarization inhibits agonist‐induced synthesis of inositol 1,4,5‐trisphosphate in rabbit mesenteric artery.
TLDR
It is suggested that membrane hyperpolarization is essential for the inhibitory action of pinacidil on the NA‐induced Ca2(+)‐releasing mechanism through an inhibition of IP3 synthesis resulting from its membranehyperpolarizing action. Expand
Motion compensation for ISAR via centroid tracking
A compensation method of target radial motion is formulated and applied to obtain focused images in inverse synthetic aperture radar (ISAR). The basic scheme is to estimate the radial motion of the… Expand
Effects of modulators of myosin light-chain kinase activity in single smooth muscle cells
TLDR
Results provide a direct demonstration at the level of a single cell that activation of the calmodulin–MLCK pathway is both necessary and sufficient to trigger contraction of smooth muscle. Expand
Effects of protamine on vascular smooth muscle of rabbit mesenteric artery.
TLDR
It is concluded that protamine exerts its inhibition on vascular smooth muscles in both an endothelium-dependent and -independent manner, and direct smooth muscle effects are due to the inhibition of both Ca(2+)-influx and the NE-induced Ca2+ release from intracellular stores. Expand
Characteristic features of noradrenaline‐induced Ca2+ mobilization and tension in arterial smooth muscle of the rabbit.
TLDR
The results suggest that NAd increases the sensitivity of contractile proteins to Ca2+ in smooth muscle of the rabbit mesenteric artery through releases from the ryanodine‐sensitive Ca 2+ storage sites. Expand
Membrane hyperpolarization inhibits agonist-induced synthesis of inositol 1,4,5-trisphosphate in rabbit mesenteric artery.
TLDR
It is suggested that membrane hyperpolarization is essential for the inhibitory action of pinacidil on the NA-induced Ca2(+)-releasing mechanism through an inhibition of IP3 synthesis resulting from its membranehyperpolarizing action. Expand
Excitation—contraction coupling in smooth muscle cells of the guinea‐pig mesenteric artery
TLDR
The excitation—contraction coupling mechanism in the smooth muscle of the guinea‐pig mesenteric artery was studied using intact and chemically skinned muscle cells to study the excitation and contraction coupling mechanism. Expand
Differences and similarities in the noradrenaline‐ and caffeine‐induced mechanical responses in the rabbit mesenteric artery
1. The properties of noradrenaline (NA)‐induced and caffeine‐induced contractions in the rabbit mesenteric artery were investigated and compared, using intact and skinned muscles.
Mechanisms of hydrogen peroxide-induced relaxation in rabbit mesenteric small artery.
TLDR
It is suggested that hydrogen peroxide induces endothelium-independent relaxation of the rabbit mesenteric small artery precontracted with norepinephrine, and may be at least in part mediated by cGMP and cyclooxygenase products in the vascular smooth muscles now used. Expand
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