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27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
It is reported that the cholesterol metabolite 27-hydroxycholesterol (27HC) stimulates MCF-7 cell xenograft growth in mice, and in ER+ breast cancer patients, 27HC content in normal breast tissue is increased compared to that in cancer-free controls, and tumor 27 HC content is further elevated. Expand
Acquiring Lexical Knowledge for Anaphora Resolution
This work discusses research aimed at improving the performance of anaphora resolution systems by acquiring the commonsense knowledge require to resolve the more complex cases ofAnaphora, such as bridging references. Expand
Endometrial preparation methods for frozen-thawed embryo transfer are associated with altered risks of hypertensive disorders of pregnancy, placenta accreta, and gestational diabetes mellitus.
Pregnancies following HRC-FET are associated with higher risks of HDPs and placenta accreta and a lower risk of GDM, and the association between the endometrium preparation method and obstetrical complication merits further attention. Expand
Assisted reproductive technology in Japan: a summary report for 2015 by The Ethics Committee of The Japan Society of Obstetrics and Gynecology
The Japan Society of Obstetrics and Gynecology implemented an assisted reproductive technology registry system in 1986 and the characteristics and treatment outcomes of ART cycles that were registered in 2015 are reported. Expand
The interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol
Recent progress is introduced in the understanding of the role of 27HC in breast cancer and cardiovascular dysfunction. Expand
Assisted reproductive technology in Japan: a summary report of 1992–2014 by the Ethics Committee, Japan Society of Obstetrics and Gynecology
The Japan Society of Obstetrics and Gynecology implemented a registry report system for the clinical practice of assisted reproductive technology in 1986. The aggregated results from 1992 to 2014 are… Expand
LXRβ/estrogen receptor-α signaling in lipid rafts preserves endothelial integrity.
- T. Ishikawa, I. Yuhanna, +4 authors M. Umetani
- Biology, Medicine
- The Journal of clinical investigation
- 1 August 2013
It is demonstrated that LXRβ has nonnuclear function in EC caveolae/lipid rafts that entails crosstalk with ERα, which promotes NO production and maintains endothelial monolayer integrity in vivo. Expand
Site-controlled InAs single quantum-dot structures on GaAs surfaces patterned by in situ electron-beam lithography
We studied a site-control technique for InAs quantum dots (QDs) on GaAs substrates using a combination of in situ electron-beam (EB) lithography and self-organized molecular-beam epitaxy. In small,… Expand
Site control of self-organized InAs dots on GaAs substrates by in situ electron-beam lithography and molecular-beam epitaxy
We studied a site-control method for self-organized InAs quantum dots on GaAs substrates by a combination of in situ electron-beam (EB) lithography and molecular-beam epitaxy (MBE) using an… Expand
Increased incidence of post-term delivery and Cesarean section after frozen-thawed embryo transfer during a hormone replacement cycle
- Kazuki Saito, K. Miyado, +8 authors H. Saito
- Journal of Assisted Reproduction and Genetics
- 20 January 2017
Patients who conceived singletons after HRC-FET were at increased risk of post-term delivery and Cesarean section compared with those who conceived after NC-Fet. Expand