A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.
An expert panel to review and develop standard terminologies and definitions related to wasting, cachexia, malnutrition, and inflammation in CKD and AKI recommends the term 'protein-energy wasting' for loss of body protein mass and fuel reserves.
The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia.
- J. Himmelfarb, P. Stenvinkel, T. Ikizler, R. Hakim
- Biology, MedicineKidney International
- 1 November 2002
The hypothesis that increased oxidative stress and its sequalae is a major contributor to increased atherosclerosis and cardiovascular morbidity and mortality found in uremia is proposed and it is proposed that retained uremic solutes such as beta-2 microglobulin, advanced glycosylated end products, cysteine, and homocysteine further contribute to the pro-atherogenic milieu of Uremia.
Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences.
Spectrum of acute renal failure in the intensive care unit: the PICARD experience.
There is a changing spectrum of ARF in the critically ill, characterized by a large burden of comorbid disease and extensive extrarenal complications, obligating the need for dialysis in the majority of patients.
Etiology of the protein-energy wasting syndrome in chronic kidney disease: a consensus statement from the International Society of Renal Nutrition and Metabolism (ISRNM).
This consensus statement of current knowledge on the etiology of PEW syndrome in CKD is provided to increase awareness, identify research needs, and provide the basis for future work to understand therapies and consequences of Pew.
Prevention and treatment of protein energy wasting in chronic kidney disease patients: a consensus statement by the International Society of Renal Nutrition and Metabolism.
In patients where oral dietary intake from regular meals cannot maintain adequate nutritional status, nutritional supplementation, administered orally, enterally, or parenterally, is shown to be effective in replenishing protein and energy stores.
KDOQI Clinical Practice Guideline for Nutrition in CKD: 2020 Update.
The 2020 update to the KDOQI Clinical Practice Guideline for Nutrition in CKD provides comprehensive up-to-date information on the understanding and care of patients with chronic kidney disease (CKD), especially in terms of their metabolic and nutritional milieu for the practicing clinician and allied health care workers.
Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease.
Evidence of increased oxidative stress and acute-phase inflammation in patients with stage 3-5 chronic kidney disease compared to healthy subjects that does not closely correlate with estimates of GFR is found.
Timing of initiation of dialysis in critically ill patients with acute kidney injury.
- Kathleen D. Liu, J. Himmelfarb, G. Chertow
- Medicine, BiologyAmerican Society of Nephrology. Clinical Journal
- 1 September 2006
Among critically ill patients with AKI, initiation of dialysis at higher BUN concentrations was associated with an increased risk for death, and these results provide a rationale for prospective testing of alternative dialysis initiation strategies in critically ill Patients with severe AKI.
Association between physical performance and all-cause mortality in CKD.
- B. Roshanravan, C. Robinson-Cohen, S. Seliger
- MedicineJournal of the American Society of Nephrology
- 1 May 2013
In older adults, measurements of physical performance assess physical function and associate with mortality and disability. Muscle wasting and diminished physical performance often accompany CKD,…