Investigations into the therapeutic effects of aerial and stem parts of Buxus papillosa C.K. Schneid.: In vitro chemical, biological and toxicological perspectives
- Hammad Saleem, T. Htar, N. Ahemad
- Medicine, ChemistryJournal of Pharmaceutical and Biomedical Analysis
- 20 March 2019
Detrimental Effects of UVB on Retinal Pigment Epithelial Cells and Its Role in Age-Related Macular Degeneration
- Camille Keisha Mahendra, Loh Teng‐Hern Tan, B. Goh
- BiologyOxidative Medicine and Cellular Longevity
- 12 August 2020
In vivo studies on the whole retina demonstrated that UVB irradiation induces gene and protein level dysregulation, indicating cellular stress and aberrations in the chromosome level, suggesting the connection of UVB damage with AMD.
ATR-FTIR and Spectrometric Methods for the Assay of Crocin in Commercial Saffron Spices (Crocus savitus L.)
- F. Y. Lee, T. Htar, G. Akowuah
- Chemistry
- 16 April 2015
Attenuated total reflectance Fourier transform infrared spectrometric method for determination of crocin in commercial saffron samples was studied. Calibration models were built based on the peaks at…
Deciphering the Binding Mechanism of Dexamethasone Against SARS-CoV-2 Main Protease: Computational Molecular Modelling Approach
The results suggest the effectiveness of Dexamethasone as potent drugs against SARS-CoV-2 since it bind tightly to its Mpro and suggest that dexamethAsone as top antiviral treatments option than the Remdesivir with high potential to fight the Sars-Cov-2.
Filago germanica (L.) Huds. bioactive constituents: Secondary metabolites fingerprinting and in vitro biological assays
- Hammad Saleem, G. Zengin, N. Ahemad
- Chemistry
- 15 September 2020
Biological, chemical and toxicological perspectives on aerial and roots of Filago germanica (L.) huds: Functional approaches for novel phyto-pharmaceuticals.
- Hammad Saleem, T. Htar, N. Ahemad
- Medicine, ChemistryFood and Chemical Toxicology
- 2019
Therapeutic propensities, phytochemical composition, and toxicological evaluation of Anagallis arvensis (L.): A wild edible medicinal food plant.
- Hammad Saleem, G. Zengin, N. Ahemad
- Medicine, ChemistryFood Research International
- 9 September 2020
Is Curcumin the Answer to Future Chemotherapy Cocktail?
Curcumin combination treatments were found to enhance anticancer effects, mediated by the multitargeting of several signalling pathways by curcumin and the co-administered cancer therapies.
Chromatographic Separation of Vitamin E Enantiomers
- J. Fu, T. Htar, Leanne de Silva, Doryn Meam-Yee Tan, L. Chuah
- ChemistryMolecules
- 1 February 2017
In this review, a few chromatographic methods that had been used to separate the stereoisomers of tocopherols and tocotrienols are discussed including high performance liquid chromatography, gas chromatography and combination of both.
HPLC–PDA Polyphenolic Quantification, UHPLC–MS Secondary Metabolite Composition, and In Vitro Enzyme Inhibition Potential of Bougainvillea glabra
- Hammad Saleem, T. Htar, N. Ahemad
- Medicine, ChemistryPlants
- 1 March 2020
B. glabra could be regarded as a perspective starting material for designing novel pharmaceuticals based on its phytochemical composition and enzyme inhibition potential against key enzymes involved in diabetes, skin problems, and inflammatory disorders.
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