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Loss of the sarcoglycan complex and sarcospan leads to muscular dystrophy in beta-sarcoglycan-deficient mice.
- K. Araishi, T. Sasaoka, +6 authors E. Ozawa
- Biology, Medicine
- Human molecular genetics
- 1 September 1999
beta-Sarcoglycan, one of the subunits of the sarcoglycan complex, is a transmembranous glycoprotein which associates with dystrophin and is the molecule responsible for beta-sarcoglycanopathy, a… Expand
CPEB2, A Novel Putative Translational Regulator in Mouse Haploid Germ Cells1
- Y. Kurihara, Motoyuki Tokuriki, +7 authors S. Uesugi
- Medicine, Biology
- Biology of reproduction
- 1 July 2003
Abstract Translational control of specific mRNAs by cytoplasmic polyadenylation has fundamental roles in gametogenesis. The cytoplasmic polyadenylation element binding (CPEB) protein regulates… Expand
Drug-metabolising enzymes are down-regulated by hypoxia in differentiated human hepatoma HepaRG cells: HIF-1alpha involvement in CYP3A4 repression.
Weak blood irrigation within solid tumours including hepatocellular carcinomas (HCCs) plays an important role in resistance to anticancer drugs by decreasing accessibility of cytotoxic agents to… Expand
Mice Deficient for a Small Cluster of Piwi-Interacting RNAs Implicate Piwi-Interacting RNAs in Transposon Control1
Abstract The mammalian testis expresses a class of small noncoding RNAs that interact with mammalian PIWI proteins. In mice, the PIWI-interacting RNAs (piRNAs) partner with mammalian PIWI proteins,… Expand
The ultrastructure of the flagellar root system of Isochrysis galbana (Prymnesiophyta)
The fine structure of the flagellar root system of Isochrysis galbana Parke (Prymnesiophyta) has been investigated and a reconstruction is presented. Associated with the left basal body and arising… Expand
Virus-induced cell death in plants expressing the mammalian 2′,5′ oligoadenylate system
The major components of the 2-5A system, responsible for the mammalian interferon-induced antiviral response, are the 2′,5′ oligoadenylate synthetase (2-5Aase) and 2′,5′ oligoadenylate (2-5A)… Expand
Expression of an Erwinia phytoene desaturase gene not only confers multiple resistance to herbicides interfering with carotenoid biosynthesis but also alters xanthophyll metabolism in transgenic…
Imino proton NMR analysis of HDV ribozymes: nested double pseudoknot structure and Mg2+ ion-binding site close to the catalytic core in solution.
- Yoichiro Tanaka, T. Hori, +4 authors S. Uesugi
- Biology, Medicine
- Nucleic acids research
- 1 February 2002
Minimized trans-acting HDV ribozyme systems consisting of three (Rz-3) and two (Rz-2) RNA strands were prepared and their folding conformations were analyzed by NMR spectroscopy. The guanosine… Expand
The RNA ligands for mouse proline-rich RNA-binding protein (mouse Prrp) contain two consensus sequences in separate loop structure
Mouse proline-rich RNA-binding protein (mPrrp) is a mouse ortholog of Xenopus Prrp, which binds to a vegetal localization element (VLE) in the 3′-untranslated region (3′-UTR) of Vg1 mRNA and is… Expand
The fine structure of mitosis in Pavlova (Prymnesiophyceae)
The ultrastructure of mitosis in the algal flagellates Pavlova lutheri and P. salina has been examined, the observations have been compared with those reported previously from other species included… Expand