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Fundamentals of Protein NMR Spectroscopy
List of Figures. List of Tables. 1. Introduction To NMR Spectroscopy. 2. Acquiring One-Dimensional Spectra. 3. Processing One-Dimensional Spectra. 4. Quantum Mechanical Description Of NMR. 5. Quantum…
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In situ labeling of immune cells with iron oxide particles: an approach to detect organ rejection by cellular MRI.
TLDR
A noninvasive approach using MRI to detect graft rejection after solid organ transplantation and the feasibility of imaging individual macrophages in vivo by MRI in a rodent heterotopic working-heart transplantation model using a more sensitive contrast agent, the micrometer-sized paramagnetic iron oxide particle, is presented.
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Magnetic Resonance Imaging Assessment of Regional Cerebral Blood Flow after Asphyxial Cardiac Arrest in Immature Rats
TLDR
ASL-MRI assessment of CBF after asphyxial Ca in PND 17 rats reveals marked duration and region-specific reperfusion patterns and identifies possible new therapeutic targets.
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Accelerated fluorine‐19 MRI cell tracking using compressed sensing
TLDR
Three‐dimensional compressed sensing 19F MRI methods are applied to quantify the macrophage burden in a localized wounding‐inflammation mouse model in vivo; at 8‐fold image acceleration, the 19F signal distribution was accurately reproduced, with no loss in signal‐to‐noise ratio.
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MRI detection of macrophages labeled using micrometer‐sized iron oxide particles
To evaluate cellular labeling of immune cells using micron‐sized iron oxide particles (MPIOs) and evaluate the MR relaxivity and MRI detection of the labeled cells.
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Real-time cardiac MRI without triggering, gating, or breath holding
TLDR
This paper demonstrates that this dynamic imaging method based on Partially Separable Function (PSF) theory can be used in the study of transplanted rat hearts for both anatomical and perfusion applications.
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MONTE: An automated Monte Carlo based approach to nuclear magnetic resonance assignment of proteins
TLDR
A general-purpose Monte Carlo assignment program has been developed to aid in the assignment of NMR resonances from proteins and can be also be used as an interactive research tool to assist in the choice of additional experimental data to facilitate completion of assignments.
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A non-invasive approach to detecting organ rejection by MRI: monitoring the accumulation of immune cells at the transplanted organ.
TLDR
MRI techniques to monitor the accumulation of immune cells at the transplanted organ as a means to detect graft rejection are developed, showing excellent correlation among the MRI signal intensity due to the USPIO-labeled macrophages at the rejecting graft.
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Aberrant ER Stress Induced Neuronal-IFNβ Elicits White Matter Injury Due to Microglial Activation and T-Cell Infiltration after TBI
TLDR
This study suggests that induction of PERK phosphorylation, a characteristic feature of ER stress is responsible for an increase in neuronal IFNβ, which, in turn, activates microglial cells and subsequently manifests the infiltration of T cells to induce neuroinflammation and subsequently white matter injury.
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High-resolution cardiac MRI using partially separable functions and weighted spatial smoothness regularization
TLDR
This paper proposes a method to improve the SNR and reduce artifacts in PSF-based reconstructions through the use of anatomical constraints obtained from a high-SNR image of composite (k, t)-space data and used to regularize the PSF reconstruction.
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