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Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a
Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers aExpand
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The mitochondrial genome of Onchocerca volvulus: sequence, structure and phylogenetic analysis.
The complete DNA sequence of the mitochondrial genome of Onchocerca volvulus is described. The O. volvulus mitochondrial genome is 13747 bp, slightly smaller than the mitochondrial genomes of theExpand
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Identification of mosquito avian-derived blood meals by polymerase chain reaction-heteroduplex analysis.
A polymerase chain reaction (PCR) heteroduplex assay (HDA) was developed to identify avian derived mosquito blood meals to the species level. The assay used primers amplifying a fragment of theExpand
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Brugia malayi: transient transfection by microinjection and particle bombardment.
To develop a method for the introduction of DNA into filarial parasites, several methods that have proven successful in other organisms were evaluated for their ability to transform Brugia malayi.Expand
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Interruption of Onchocerca volvulus transmission in the Abu Hamed focus, Sudan.
Abu Hamed, Sudan, the northernmost location of onchocerciasis in the world, began community-directed treatment with ivermectin (CDTI) in 1998, with annual treatments enhanced to semiannual in 2007.Expand
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Wolbachia endosymbiont levels in severe and mild strains of Onchocerca volvulus.
Epidemiological, clinical and genetic data have all suggested that the filarial parasite Onchocerca volvulus, the causative agent of onchocerciasis (or river blindness) exists as two strains in WestExpand
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The First Confirmed Elimination of an Onchocerciasis Focus in Africa: Abu Hamed, Sudan.
Mass treatment with ivermectin for onchocerciasis was stopped in 2012 in Abu Hamed, an isolated focus on the River Nile in northern Sudan. A 3-year posttreatment surveillance (PTS) ensued, at the endExpand
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PCR Detection of Clostridium difficile and its Toxigenic Strains in Public Places in Southeast Ohio
Clostridium difficile is the most common infectious cause of diarrhea in hospitalized patients with increasing role for the environment as a source of contamination. In this study, we modified aExpand
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Cytotaxonomic and Molecular Analysis ofSimulium (Edwardsellum) damnosumsensu lato (Diptera: Simuliidae) from Abu Hamed, Sudan
Abstract The northernmost focus forOnchocerca volvulusLeuckhart (Nematoda: Onchocercidae), the causative agent of human onchocerciasis, is found along the Nile near the town of Abu Hamed in Sudan.Expand
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Angiogenic activity of an Onchocerca volvulus Ancylostoma secreted protein homologue.
Angiogenesis is an important step in the development of ocular onchocercaisis. In previous studies, it has been demonstrated that Onchocerca volvulus homologues of the Ancylostoma secreted proteinExpand
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