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Characterization of ionomycin as a calcium ionophore.
Measurement of the binding of Ionomycin with Ca2+ indicates that ionomycin complexes and transports calcium ion in a one to one stoichiometry.
Novel polyether antibiotics X-14868A, B, C, and D produced by a Nocardia. Discovery, fermentation, biological as well as ionophore properties and taxonomy of the producing culture.
A hitherto undescribed Nocardia culture has been isolated from an Australian soil sample and found to produce novel polyether antibiotics X-14868A, X-14868B, X-14868C and X-14868D.
X-14547A, a new ionophorous antibiotic produced by Streptomyces antibioticus NRRL 8167. Discovery, fermentation, biological properties and taxonomy of the producing culture.
X-14547A is a novel antibiotic produced by a new strain of Streptomyces antibioticus (NRRL 8167) and is capable of complexing and transporting divalent as well as monovalent metal cations.
Novel polyether antibiotics X-14873A, G and H produced by a Streptomyces: taxonomy of the producing culture, fermentation, biological and ionophorous properties of the antibiotics.
This report presents taxonomic studies and fermentation conditions for the antibiotic producing culture of Streptomyces sp.
Feedback inhibition of the synthesis of an antibiotic: aurodox (X-5108).
It was found that addition of exogenous aurodox inhibits further accumulation of auroDox by the antibiotic-producing culture and this effect was immediate and readily reversible, indicating that it could be due to inhibition of an enzyme(s) involved in the biosynthesis of a Kurodox.
Studies on a new polyether antibiotic, Ro 21-6150.
A new polyether antibiotic, Ro 21-6150, has been isolated from culture broths of Streptomyces hygroscopicus, strain X-14563. Ro 21-6150 has ionophore properties and is active in vitro against…
Laccase localized in hulle cells and cleistothecial primordia of Aspergillus nidulans
The presence of histologically detectable laccase in cleistothecial primordia provides a valuable tool, previously unavailable, for quantitating the early stages of sexual development in A. nidulans.
Preparation, properties and biological activity of natural and semisynthetic urethanes of monensin.
- J. Westley, C. Liu, R. Evans, L. H. Sello, N. Troupe, T. Hermann
- Chemistry, BiologyThe Journal of antibiotics
- 1 September 1983
The most active derivatives are the phenylurethanes which are ten times more active in vitro against Gram-positive bacteria and unlike monensin are active against Candida albicans and Penicillium digitatum.
Structure of antibiotic X-14547A, a carboxylic acid ionophore produced by Streptomyces antibioticus, NRRL 8167
Aus fermentierten Kulturen von streptomyces antibioticus wurden die Titelverbindung (I) als eins der Hauptprodukte und das neue Dihydroindolon (II) als ein Nebenprodukt isoliert.
Mutants of Aspergillus nidulans blocked at an early stage of sporulation secrete an unusual metabolite
- N. Z. Butnick, L. Yager, T. Hermann, M. Kurtz, S. Champe
- BiologyJournal of bacteriology
- 1 November 1984
The results suggest that preinduction mutants are blocked in a phenolic metabolic pathway, one or more product of which participates in the initiation of sporulation.