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The Role of L- and T-Type Calcium Channels in Local and Remote Calcium Responses in Rat Mesenteric Terminal Arterioles
Background/Aims: The roles of intercellular communication and T-type versus L-type voltage-dependent Ca2+ channels (VDCCs) in conducted vasoconstriction to local KCl-induced depolarization wereExpand
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Distinct permeation profiles of the connexin 30 and 43 hemichannels
Connexin 43 (Cx43) hemichannels may form open channels in the plasma membrane when exposed to specific stimuli, e.g. reduced extracellular concentration of divalent cations, and allow passage ofExpand
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Role of connexin40 in the autoregulatory response of the afferent arteriole.
Connexins in renal arterioles affect autoregulation of arteriolar tonus and renal blood flow and are believed to be involved in the transmission of the tubuloglomerular feedback (TGF) response acrossExpand
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  • Open Access
Phosphorylation of connexin43 on serine 306 regulates electrical coupling.
BACKGROUND Phosphorylation is a key regulatory event in controlling the function of the cardiac gap junction protein connexin43 (Cx43). Three new phosphorylation sites (S296, S297, S306) have beenExpand
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Na+‐independent, nifedipine‐resistant rat afferent arteriolar Ca2+ responses to noradrenaline: possible role of TRPC channels
Aim:  In rat afferent arterioles we investigated the role of Na+ entry in noradrenaline (NA)‐induced depolarization and voltage‐dependent Ca2+ entry together with the importance of the transientExpand
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Connexin mimetic peptides fail to inhibit vascular conducted calcium responses in renal arterioles.
Vascular conducted responses are believed to play a central role in controlling the microcirculatory blood flow. The responses most likely spread through gap junctions in the vascular wall. AtExpand
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  • Open Access
Closure of multiple types of K+ channels is necessary to induce changes in renal vascular resistance in vivo in rats
Inhibition of K+ channels might mediate renal vasoconstriction. As inhibition of a single type of K+ channel caused minor or no renal vasoconstriction in vivo in rats, we hypothesized that severalExpand
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Stimulation of aquaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress
Osmotic water permeability (Pf) was measured in spheroid-shaped human nasal airway epithelial explants pre-exposed to increasing levels of hyperosmotic stress. The fluid-filled spheroids, derivedExpand
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Myocardial impulse propagation is impaired in right ventricular tissue of Zucker Diabetic Fatty (ZDF) rats
BackgroundDiabetes increases the risk of cardiovascular complications including arrhythmias, but the underlying mechanisms remain to be established. Decreased conduction velocity (CV), which is anExpand
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KV7.4 channels participate in the control of rodent renal vascular resting tone
We tested the hypothesis that KV7 channels contribute to basal renal vascular tone and that they participate in agonist‐induced renal vasoconstriction or vasodilation.
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